Exposure of Lymphocytes to High Doses of Actinobacillus actinomycetemcomitans Cytolethal Distending Toxin Induces Rapid Onset of Apoptosis-Mediated DNA Fragmentation

von Shenker, Bruce J., Demuth, Donald R., Zekavat, Ali
Veröffentlicht 2006

A Journey of Cytolethal Distending Toxins through Cell Membranes

von Boesze-Battaglia, Kathleen, Alexander, Desiree, Dlakić, Mensur, Shenker, Bruce J.
Veröffentlicht in Front Cell Infect Microbiol (2016)

Immune Function Effects of Dental Amalgam in Children: A Randomized Clinical Trial

von Shenker, Bruce J., Maserejian, Nancy N., Zhang, Annie, McKinlay, Sonja
Veröffentlicht 2008

Lymphoid susceptibility to the Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is dependent upon baseline levels of the signaling lipid, phosphatidylinosito...

von Shenker, Bruce J., Walker, Lisa P., Zekavat, Ali, Boesze-Battaglia, Kathleen
Veröffentlicht in Mol Oral Microbiol (2015)

The Cytolethal Distending Toxin Contributes to Microbial Virulence and Disease Pathogenesis by Acting As a Tri-Perditious Toxin

von Scuron, Monika D., Boesze-Battaglia, Kathleen, Dlakić, Mensur, Shenker, Bruce J.
Veröffentlicht in Front Cell Infect Microbiol (2016)

Blockade of the PI-3K signaling pathway by the Aggregatibacter actinomycetemcomitans cytolethal distending toxin induces macrophages to synthesize and secrete pro-inflammatory cyto...

von Shenker, Bruce J., Walker, Lisa P., Zekavat, Ali, Dlakić, Mensur, Boesze-Battaglia, Kathleen
Veröffentlicht 2014

Internalization and Intoxication of Human Macrophages by the Active Subunit of the Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Is Dependent Upon Cellugyrin (S...

von Boesze-Battaglia, Kathleen, Dhingra, Anuradha, Walker, Lisa M., Zekavat, Ali, Shenker, Bruce J.
Veröffentlicht in Front Immunol (2020)

Actinobacillus actinomycetemcomitans Leukotoxin Induces Apoptosis in HL-60 Cells

von Korostoff, Jonathan, Wang, Jian Fei, Kieba, Irene, Miller, Mark, Shenker, Bruce J., Lally, Edward T.
Veröffentlicht 1998

Inhibition of mast cell degranulation by a chimeric toxin containing a novel phosphatidylinositol-3,4,5-triphosphate phosphatase

von Shenker, Bruce J., Boesze-Battaglia, Kathleen, Zekavat, Ali, Walker, Lisa, Besack, Dave, Ali, Hydar
Veröffentlicht 2010

The Cell-Cycle Regulatory Protein p21(CIP1/WAF1) Is Required for Cytolethal Distending Toxin (Cdt)-Induced Apoptosis

von Shenker, Bruce J., Walker, Lisa M., Zekavat, Ali, Weiss, Robert H., Boesze-Battaglia, Kathleen
Veröffentlicht in Pathogens (2020)

Internalization of the Active Subunit of the Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Is Dependent upon Cellugyrin (Synaptogyrin 2), a Host Cell Non-Neuron...

von Boesze-Battaglia, Kathleen, Walker, Lisa P., Dhingra, Anuradha, Kandror, Konstantin, Tang, Hsin-Yao, Shenker, Bruce J.
Veröffentlicht in Front Cell Infect Microbiol (2017)

Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Activates the NLRP3 Inflammasome in Human Macrophages, Leading to the Release of Proinflammatory Cytokines

von Shenker, Bruce J., Ojcius, David M., Walker, Lisa P., Zekavat, Ali, Scuron, Monika Damek, Boesze-Battaglia, Kathleen
Veröffentlicht in Infect Immun (2015)

Cytolethal distending toxin-induced release of interleukin-1β by human macrophages is dependent upon activation of glycogen synthase kinase (GSK) 3β, spleen tyrosine kinase (Syk) a...

von Shenker, Bruce J, Walker, Lisa M., Zekavat, Zeyed, Ojcius, David M., Huang, Pei-Rong, Boesze-Battaglia, Kathleen
Veröffentlicht in Cell Microbiol (2020)

Cytolethal Distending Toxin-induced Cell Cycle Arrest of Lymphocytes Is Dependent upon Recognition and Binding to Cholesterol

von Boesze-Battaglia, Kathleen, Brown, Angela, Walker, Lisa, Besack, Dave, Zekavat, Ali, Wrenn, Steve, Krummenacher, Claude, Shenker, Bruce J.
Veröffentlicht 2009

A Novel Mode of Action for a Microbial-Derived Immunotoxin: The Cytolethal Distending Toxin Subunit B Exhibits Phosphatidylinositol 3,4,5-Triphosphate Phosphatase Activity()

von Shenker, Bruce J., Dlakić, Mensur, Walker, Lisa P., Besack, Dave, Jaffe, Eileen, LaBelle, Ed, Boesze-Battaglia, Kathleen
Veröffentlicht in J Immunol (2007)

The Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Active Subunit CdtB Contains a Cholesterol Recognition Sequence Required for Toxin Binding and Subunit Interna...

von Boesze-Battaglia, Kathleen, Walker, Lisa P., Zekavat, Ali, Dlakić, Mensur, Scuron, Monika Damek, Nygren, Patrik, Shenker, Bruce J.
Veröffentlicht in Infect Immun (2015)

Cholesterol-rich membrane microdomains mediate cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal-distending toxin

von Boesze-Battaglia, Kathleen, Besack, Dave, McKay, Terry, Zekavat, Ali, Otis, Linda, Jordan-Sciutto, Kelly, Shenker, Bruce J.
Veröffentlicht in Cell Microbiol (2006)

The Active Subunit of the Cytolethal Distending Toxin, CdtB, Derived From Both Haemophilus ducreyi and Campylobacter jejuni Exhibits Potent Phosphatidylinositol-3,4,5-Triphosphate...

von Huang, Grace, Boesze-Battaglia, Kathleen, Walker, Lisa P., Zekavat, Ali, Schaefer, Zachary P., Blanke, Steven R., Shenker, Bruce J.
Veröffentlicht in Front Cell Infect Microbiol (2021)