The Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Active Subunit CdtB Contains a Cholesterol Recognition Sequence Required for Toxin Binding and Subunit Internalization

Induction of cell cycle arrest in lymphocytes following exposure to the Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is dependent upon the integrity of lipid membrane microdomains. Moreover, we have previously demonstrated that the association of Cdt with target cells invo...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Boesze-Battaglia, Kathleen, Walker, Lisa P., Zekavat, Ali, Dlakić, Mensur, Scuron, Monika Damek, Nygren, Patrik, Shenker, Bruce J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567645/
https://ncbi.nlm.nih.gov/pubmed/26216427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00788-15
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