The Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Active Subunit CdtB Contains a Cholesterol Recognition Sequence Required for Toxin Binding and Subunit Internalization

Induction of cell cycle arrest in lymphocytes following exposure to the Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is dependent upon the integrity of lipid membrane microdomains. Moreover, we have previously demonstrated that the association of Cdt with target cells invo...

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Publicado en:Infect Immun
Autores principales: Boesze-Battaglia, Kathleen, Walker, Lisa P., Zekavat, Ali, Dlakić, Mensur, Scuron, Monika Damek, Nygren, Patrik, Shenker, Bruce J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567645/
https://ncbi.nlm.nih.gov/pubmed/26216427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00788-15
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