Exposure of Lymphocytes to High Doses of Actinobacillus actinomycetemcomitans Cytolethal Distending Toxin Induces Rapid Onset of Apoptosis-Mediated DNA Fragmentation

le Shenker, Bruce J., Demuth, Donald R., Zekavat, Ali
Foilsithe 2006

Lymphoid susceptibility to the Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is dependent upon baseline levels of the signaling lipid, phosphatidylinosito...

le Shenker, Bruce J., Walker, Lisa P., Zekavat, Ali, Boesze-Battaglia, Kathleen
Foilsithe in Mol Oral Microbiol (2015)

Blockade of the PI-3K signaling pathway by the Aggregatibacter actinomycetemcomitans cytolethal distending toxin induces macrophages to synthesize and secrete pro-inflammatory cyto...

le Shenker, Bruce J., Walker, Lisa P., Zekavat, Ali, Dlakić, Mensur, Boesze-Battaglia, Kathleen
Foilsithe 2014

Internalization and Intoxication of Human Macrophages by the Active Subunit of the Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Is Dependent Upon Cellugyrin (S...

le Boesze-Battaglia, Kathleen, Dhingra, Anuradha, Walker, Lisa M., Zekavat, Ali, Shenker, Bruce J.
Foilsithe in Front Immunol (2020)

Inhibition of mast cell degranulation by a chimeric toxin containing a novel phosphatidylinositol-3,4,5-triphosphate phosphatase

le Shenker, Bruce J., Boesze-Battaglia, Kathleen, Zekavat, Ali, Walker, Lisa, Besack, Dave, Ali, Hydar
Foilsithe 2010

The Cell-Cycle Regulatory Protein p21(CIP1/WAF1) Is Required for Cytolethal Distending Toxin (Cdt)-Induced Apoptosis

le Shenker, Bruce J., Walker, Lisa M., Zekavat, Ali, Weiss, Robert H., Boesze-Battaglia, Kathleen
Foilsithe in Pathogens (2020)

Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Activates the NLRP3 Inflammasome in Human Macrophages, Leading to the Release of Proinflammatory Cytokines

le Shenker, Bruce J., Ojcius, David M., Walker, Lisa P., Zekavat, Ali, Scuron, Monika Damek, Boesze-Battaglia, Kathleen
Foilsithe in Infect Immun (2015)

Cytolethal Distending Toxin-induced Cell Cycle Arrest of Lymphocytes Is Dependent upon Recognition and Binding to Cholesterol

le Boesze-Battaglia, Kathleen, Brown, Angela, Walker, Lisa, Besack, Dave, Zekavat, Ali, Wrenn, Steve, Krummenacher, Claude, Shenker, Bruce J.
Foilsithe 2009

The Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Active Subunit CdtB Contains a Cholesterol Recognition Sequence Required for Toxin Binding and Subunit Interna...

le Boesze-Battaglia, Kathleen, Walker, Lisa P., Zekavat, Ali, Dlakić, Mensur, Scuron, Monika Damek, Nygren, Patrik, Shenker, Bruce J.
Foilsithe in Infect Immun (2015)

Cholesterol-rich membrane microdomains mediate cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal-distending toxin

le Boesze-Battaglia, Kathleen, Besack, Dave, McKay, Terry, Zekavat, Ali, Otis, Linda, Jordan-Sciutto, Kelly, Shenker, Bruce J.
Foilsithe in Cell Microbiol (2006)

The Active Subunit of the Cytolethal Distending Toxin, CdtB, Derived From Both Haemophilus ducreyi and Campylobacter jejuni Exhibits Potent Phosphatidylinositol-3,4,5-Triphosphate...

le Huang, Grace, Boesze-Battaglia, Kathleen, Walker, Lisa P., Zekavat, Ali, Schaefer, Zachary P., Blanke, Steven R., Shenker, Bruce J.
Foilsithe in Front Cell Infect Microbiol (2021)