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Cholesterol-rich membrane microdomains mediate cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal-distending toxin

We have previously shown that Actinobacillus actinomycetemcomitans cytolethal-distending toxin (Cdt) is a potent immunosuppressive agent that induces G2/M arrest in human lymphocytes. In this study, we explored the possibility that Cdt-mediated immunotoxicity involves lipid membrane microdomains. We...

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Detalhes bibliográficos
Publicado no:Cell Microbiol
Main Authors: Boesze-Battaglia, Kathleen, Besack, Dave, McKay, Terry, Zekavat, Ali, Otis, Linda, Jordan-Sciutto, Kelly, Shenker, Bruce J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732718/
https://ncbi.nlm.nih.gov/pubmed/16611231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2005.00669.x
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