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Cytolethal Distending Toxin-induced Cell Cycle Arrest of Lymphocytes Is Dependent upon Recognition and Binding to Cholesterol

Induction of cell cycle arrest in lymphocytes after exposure to the Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is dependent upon the integrity of lipid membrane microdomains. In this study we further demonstrate that the association of Cdt with lymphocyte plasma membrane...

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Autors principals: Boesze-Battaglia, Kathleen, Brown, Angela, Walker, Lisa, Besack, Dave, Zekavat, Ali, Wrenn, Steve, Krummenacher, Claude, Shenker, Bruce J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667752/
https://ncbi.nlm.nih.gov/pubmed/19240023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809094200
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