Cytolethal Distending Toxin-induced Cell Cycle Arrest of Lymphocytes Is Dependent upon Recognition and Binding to Cholesterol

Induction of cell cycle arrest in lymphocytes after exposure to the Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is dependent upon the integrity of lipid membrane microdomains. In this study we further demonstrate that the association of Cdt with lymphocyte plasma membrane...

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Hauptverfasser: Boesze-Battaglia, Kathleen, Brown, Angela, Walker, Lisa, Besack, Dave, Zekavat, Ali, Wrenn, Steve, Krummenacher, Claude, Shenker, Bruce J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667752/
https://ncbi.nlm.nih.gov/pubmed/19240023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809094200
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