Exposure of Lymphocytes to High Doses of Actinobacillus actinomycetemcomitans Cytolethal Distending Toxin Induces Rapid Onset of Apoptosis-Mediated DNA Fragmentation

Por Shenker, Bruce J., Demuth, Donald R., Zekavat, Ali
Publicado em 2006

A Journey of Cytolethal Distending Toxins through Cell Membranes

Por Boesze-Battaglia, Kathleen, Alexander, Desiree, Dlakić, Mensur, Shenker, Bruce J.
Publicado no Front Cell Infect Microbiol (2016)

Immune Function Effects of Dental Amalgam in Children: A Randomized Clinical Trial

Por Shenker, Bruce J., Maserejian, Nancy N., Zhang, Annie, McKinlay, Sonja
Publicado em 2008

Lymphoid susceptibility to the Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is dependent upon baseline levels of the signaling lipid, phosphatidylinosito...

Por Shenker, Bruce J., Walker, Lisa P., Zekavat, Ali, Boesze-Battaglia, Kathleen
Publicado no Mol Oral Microbiol (2015)

The Cytolethal Distending Toxin Contributes to Microbial Virulence and Disease Pathogenesis by Acting As a Tri-Perditious Toxin

Por Scuron, Monika D., Boesze-Battaglia, Kathleen, Dlakić, Mensur, Shenker, Bruce J.
Publicado no Front Cell Infect Microbiol (2016)

Blockade of the PI-3K signaling pathway by the Aggregatibacter actinomycetemcomitans cytolethal distending toxin induces macrophages to synthesize and secrete pro-inflammatory cyto...

Por Shenker, Bruce J., Walker, Lisa P., Zekavat, Ali, Dlakić, Mensur, Boesze-Battaglia, Kathleen
Publicado em 2014

Internalization and Intoxication of Human Macrophages by the Active Subunit of the Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Is Dependent Upon Cellugyrin (S...

Por Boesze-Battaglia, Kathleen, Dhingra, Anuradha, Walker, Lisa M., Zekavat, Ali, Shenker, Bruce J.
Publicado no Front Immunol (2020)

Actinobacillus actinomycetemcomitans Leukotoxin Induces Apoptosis in HL-60 Cells

Por Korostoff, Jonathan, Wang, Jian Fei, Kieba, Irene, Miller, Mark, Shenker, Bruce J., Lally, Edward T.
Publicado em 1998

Inhibition of mast cell degranulation by a chimeric toxin containing a novel phosphatidylinositol-3,4,5-triphosphate phosphatase

Por Shenker, Bruce J., Boesze-Battaglia, Kathleen, Zekavat, Ali, Walker, Lisa, Besack, Dave, Ali, Hydar
Publicado em 2010

The Cell-Cycle Regulatory Protein p21(CIP1/WAF1) Is Required for Cytolethal Distending Toxin (Cdt)-Induced Apoptosis

Por Shenker, Bruce J., Walker, Lisa M., Zekavat, Ali, Weiss, Robert H., Boesze-Battaglia, Kathleen
Publicado no Pathogens (2020)

Internalization of the Active Subunit of the Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Is Dependent upon Cellugyrin (Synaptogyrin 2), a Host Cell Non-Neuron...

Por Boesze-Battaglia, Kathleen, Walker, Lisa P., Dhingra, Anuradha, Kandror, Konstantin, Tang, Hsin-Yao, Shenker, Bruce J.
Publicado no Front Cell Infect Microbiol (2017)

Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Activates the NLRP3 Inflammasome in Human Macrophages, Leading to the Release of Proinflammatory Cytokines

Por Shenker, Bruce J., Ojcius, David M., Walker, Lisa P., Zekavat, Ali, Scuron, Monika Damek, Boesze-Battaglia, Kathleen
Publicado no Infect Immun (2015)

Cytolethal distending toxin-induced release of interleukin-1β by human macrophages is dependent upon activation of glycogen synthase kinase (GSK) 3β, spleen tyrosine kinase (Syk) a...

Por Shenker, Bruce J, Walker, Lisa M., Zekavat, Zeyed, Ojcius, David M., Huang, Pei-Rong, Boesze-Battaglia, Kathleen
Publicado no Cell Microbiol (2020)

Cytolethal Distending Toxin-induced Cell Cycle Arrest of Lymphocytes Is Dependent upon Recognition and Binding to Cholesterol

Por Boesze-Battaglia, Kathleen, Brown, Angela, Walker, Lisa, Besack, Dave, Zekavat, Ali, Wrenn, Steve, Krummenacher, Claude, Shenker, Bruce J.
Publicado em 2009

A Novel Mode of Action for a Microbial-Derived Immunotoxin: The Cytolethal Distending Toxin Subunit B Exhibits Phosphatidylinositol 3,4,5-Triphosphate Phosphatase Activity()

Por Shenker, Bruce J., Dlakić, Mensur, Walker, Lisa P., Besack, Dave, Jaffe, Eileen, LaBelle, Ed, Boesze-Battaglia, Kathleen
Publicado no J Immunol (2007)

The Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Active Subunit CdtB Contains a Cholesterol Recognition Sequence Required for Toxin Binding and Subunit Interna...

Por Boesze-Battaglia, Kathleen, Walker, Lisa P., Zekavat, Ali, Dlakić, Mensur, Scuron, Monika Damek, Nygren, Patrik, Shenker, Bruce J.
Publicado no Infect Immun (2015)

Cholesterol-rich membrane microdomains mediate cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal-distending toxin

Por Boesze-Battaglia, Kathleen, Besack, Dave, McKay, Terry, Zekavat, Ali, Otis, Linda, Jordan-Sciutto, Kelly, Shenker, Bruce J.
Publicado no Cell Microbiol (2006)