Internalization of the Active Subunit of the Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Is Dependent upon Cellugyrin (Synaptogyrin 2), a Host Cell Non-Neuronal Paralog of the Synaptic Vesicle Protein, Synaptogyrin 1

The Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is a heterotrimeric AB(2) toxin capable of inducing lymphocytes, and other cell types, to undergo cell cycle arrest and apoptosis. Exposure to Cdt results in binding to the cell surface followed by internalization and transl...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Front Cell Infect Microbiol
Hlavní autoři: Boesze-Battaglia, Kathleen, Walker, Lisa P., Dhingra, Anuradha, Kandror, Konstantin, Tang, Hsin-Yao, Shenker, Bruce J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694546/
https://ncbi.nlm.nih.gov/pubmed/29184850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00469
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky