A Novel Mode of Action for a Microbial-Derived Immunotoxin: The Cytolethal Distending Toxin Subunit B Exhibits Phosphatidylinositol 3,4,5-Triphosphate Phosphatase Activity()

The Actinobacillus actinomycetemcomitans cytolethal distending toxin (Cdt) is a potent immunotoxin that induces G(2) arrest in human lymphocytes. We now show that the CdtB subunit exhibits phosphatidylinositol (PI)-3,4,5-triphosphate phosphatase activity. Breakdown product analysis indicates that Cd...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Immunol
Principais autores: Shenker, Bruce J., Dlakić, Mensur, Walker, Lisa P., Besack, Dave, Jaffe, Eileen, LaBelle, Ed, Boesze-Battaglia, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472023/
https://ncbi.nlm.nih.gov/pubmed/17404292
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados