Antibody engineering & therapeutics, the annual meeting of the antibody society December 7–10, 2015, San Diego, CA, USA

by Pauthner, Matthias, Yeung, Jenny, Ullman, Chris, Bakker, Joost, Wurch, Thierry, Reichert, Janice M., Lund-Johansen, Fridtjof, Bradbury, Andrew R.M., Carter, Paul J., Melis, Joost P.M.
Published in MAbs (2016)

Global site-specific analysis of glycoprotein N-glycan processing

by Cao, Liwei, Diedrich, Jolene K, Ma, Yuanhui, Wang, Nianshuang, Pauthner, Matthias, Park, Sung-Kyu Robin, Delahunty, Claire M, McLellan, Jason S, Burton, Dennis R, Yates, John R, Paulson, James C
Published in Nat Protoc (2018)

Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization

by Bianchi, Matteo, Turner, Hannah L., Nogal, Bartek, Cottrell, Christopher A., Oyen, David, Pauthner, Matthias, Bastidas, Raiza, Nedellec, Rebecca, McCoy, Laura E., Wilson, Ian A., Burton, Dennis R., Ward, Andrew B., Hangartner, Lars
Published in Immunity (2018)

Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques

by Zhao, Fangzhu, Joyce, Collin, Burns, Alison, Nogal, Bartek, Cottrell, Christopher A., Ramos, Alejandra, Biddle, Trevor, Pauthner, Matthias, Nedellec, Rebecca, Qureshi, Huma, Mason, Rosemarie, Landais, Elise, Briney, Bryan, Ward, Andrew B., Burton, Dennis R., Sok, Devin
Published in Cell Rep (2020)

Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers

by Carnathan, Diane G., Kaushik, Kirti, Ellebedy, Ali H., Enemuo, Chiamaka A., Gebru, Etse H., Dhadvai, Pallavi, Rasheed, Mohammed Ata Ur, Pauthner, Matthias G., Ozorowski, Gabriel, Ahmed, Rafi, Burton, Dennis R., Ward, Andrew B., Silvestri, Guido, Crotty, Shane, Locci, Michela
Published in Front Immunol (2020)

Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen

by Jardine, Joseph G., Ota, Takayuki, Sok, Devin, Pauthner, Matthias, Kulp, Daniel W., Kalyuzhniy, Oleksandr, Skog, Patrick D., Thinnes, Theresa C., Bhullar, Deepika, Briney, Bryan, Menis, Sergey, Jones, Meaghan, Kubitz, Mike, Spencer, Skye, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Nemazee, David
Published in Science (2015)

HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite

by Nogal, Bartek, McCoy, Laura E., van Gils, Marit J., Cottrell, Christopher A., Voss, James E., Andrabi, Raiees, Pauthner, Matthias, Liang, Chi-Hui, Messmer, Terrence, Nedellec, Rebecca, Shin, Mia, Turner, Hannah L., Ozorowski, Gabriel, Sanders, Rogier W., Burton, Dennis R., Ward, Andrew B.
Published in Sci Adv (2020)

Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits

by Yang, Yuhe R., McCoy, Laura E., van Gils, Marit J., Andrabi, Raiees, Turner, Hannah L., Yuan, Meng, Cottrell, Christopher A., Ozorowski, Gabriel, Voss, James, Pauthner, Matthias, Polveroni, Thomas M., Messmer, Terrence, Wilson, Ian A., Sanders, Rogier W., Burton, Dennis R., Ward, Andrew B.
Published in J Virol (2020)

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

by Sok, Devin, van Gils, Marit J., Pauthner, Matthias, Julien, Jean-Philippe, Saye-Francisco, Karen L., Hsueh, Jessica, Briney, Bryan, Lee, Jeong Hyun, Le, Khoa M., Lee, Peter S., Hua, Yuanzi, Seaman, Michael S., Moore, John P., Ward, Andrew B., Wilson, Ian A., Sanders, Rogier W., Burton, Dennis R.
Published in Proc Natl Acad Sci U S A (2014)

A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

by Lee, Jeong Hyun, Andrabi, Raiees, Su, Ching-Yao, Yasmeen, Anila, Julien, Jean-Philippe, Kong, Leopold, Wu, Nicholas C., McBride, Ryan, Sok, Devin, Pauthner, Matthias, Cottrell, Christopher A., Nieusma, Travis, Blattner, Claudia, Paulson, James C., Klasse, Per Johan, Wilson, Ian A., Burton, Dennis R., Ward, Andrew B.
Published in Immunity (2017)

Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

by Sok, Devin, Briney, Bryan, Jardine, Joseph G., Kulp, Daniel W., Menis, Sergey, Pauthner, Matthias, Wood, Andrew, Lee, E-Chiang, Le, Khoa M., Jones, Meaghan, Ramos, Alejandra, Kalyuzhniy, Oleksandr, Adachi, Yumiko, Kubitz, Michael, MacPherson, Skye, Bradley, Allan, Friedrich, Glenn A., Schief, William R., Burton, Dennis R.
Published in Science (2016)

Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer

by Cao, Liwei, Pauthner, Matthias, Andrabi, Raiees, Rantalainen, Kimmo, Berndsen, Zachary, Diedrich, Jolene K., Menis, Sergey, Sok, Devin, Bastidas, Raiza, Park, Sung-Kyu Robin, Delahunty, Claire M., He, Lin, Guenaga, Javier, Wyatt, Richard T., Schief, William R., Ward, Andrew B., Yates, John R., Burton, Dennis R., Paulson, James C.
Published in Nat Commun (2018)

Rectal Acquisition of Simian Immunodeficiency Virus (SIV) SIVmac239 Infection despite Vaccine-Induced Immune Responses against the Entire SIV Proteome

by Martins, Mauricio A., Gonzalez-Nieto, Lucas, Ricciardi, Michael J., Bailey, Varian K., Dang, Christine M., Bischof, Georg F., Pedreño-Lopez, Nuria, Pauthner, Matthias G., Burton, Dennis R., Parks, Christopher L., Earl, Patricia, Moss, Bernard, Rakasz, Eva G., Lifson, Jeffrey D., Desrosiers, Ronald C., Watkins, David I.
Published in J Virol (2020)

Global site-specific N-glycosylation analysis of HIV envelope glycoprotein

by Cao, Liwei, Diedrich, Jolene K., Kulp, Daniel W., Pauthner, Matthias, He, Lin, Park, Sung-Kyu Robin, Sok, Devin, Su, Ching Yao, Delahunty, Claire M., Menis, Sergey, Andrabi, Raiees, Guenaga, Javier, Georgeson, Erik, Kubitz, Michael, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Yates III, John R., Paulson, James C.
Published in Nat Commun (2017)

The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template

by Andrabi, Raiees, Pallesen, Jesper, Allen, Joel D., Song, Ge, Zhang, Jinsong, de Val, Natalia, Gegg, Gavin, Porter, Katelyn, Su, Ching-Yao, Pauthner, Matthias, Newman, Amanda, Bouton-Verville, Hilary, Garces, Fernando, Wilson, Ian A., Crispin, Max, Hahn, Beatrice H., Haynes, Barton F., Verkoczy, Laurent, Ward, Andrew B., Burton, Dennis R.
Published in Cell Rep (2019)

Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies

by McCoy, Laura E, van Gils, Marit J, Ozorowski, Gabriel, Messmer, Terrence, Briney, Bryan, Voss, James E, Kulp, Daniel W, Macauley, Matthew S, Sok, Devin, Pauthner, Matthias, Menis, Sergey, Cottrell, Christopher A, Torres, Jonathan L, Hsueh, Jessica, Schief, William R, Wilson, Ian A, Ward, Andrew B, Sanders, Rogier W, Burton, Dennis R
Published in Cell Rep (2016)

Infection of Monkeys by Simian-human Immunodeficiency Viruses with Transmitted/ founder Clade C HIV-1 Envelopes

by Asmal, Mohammed, Luedemann, Corinne, Lavine, Christy L., Mach, Linh V., Balachandran, Harikrishnan, Brinkley, Christie, Denny, Thomas N., Lewis, Mark G., Anderson, Hanne, Pal, Ranajit, Sok, Devin, Le, Khoa, Pauthner, Matthias, Hahn, Beatrice H., Shaw, George M., Seaman, Michael S., Letvin, Norman L., Burton, Dennis R., Sodroski, Joseph G., Haynes, Barton F., Santra, Sampa
Published in Virology (2014)

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

by Kulp, Daniel W., Steichen, Jon M., Pauthner, Matthias, Hu, Xiaozhen, Schiffner, Torben, Liguori, Alessia, Cottrell, Christopher A., Havenar-Daughton, Colin, Ozorowski, Gabriel, Georgeson, Erik, Kalyuzhniy, Oleksandr, Willis, Jordan R., Kubitz, Michael, Adachi, Yumiko, Reiss, Samantha M., Shin, Mia, de Val, Natalia, Ward, Andrew B., Crotty, Shane, Burton, Dennis R., Schief, William R.
Published in Nat Commun (2017)

A meta-analysis of passive immunization studies shows an association of serum neutralizing antibody titer with protection against SHIV challenge

by Pegu, Amarendra, Borate, Bhavesh, Huang, Yunda, Pauthner, Matthias G., Hessell, Ann J., Julg, Boris, Doria-Rose, Nicole A., Schmidt, Stephen D., Carpp, Lindsay N., Cully, Michelle D., Chen, Xuejun, Shaw, George M., Barouch, Dan H., Haigwood, Nancy L., Corey, Lawrence, Burton, Dennis R., Roederer, Mario, Gilbert, Peter B., Mascola, John R., Huang, Ying
Published in Cell Host Microbe (2019)

A prominent site of antibody vulnerability on HIV envelope incorporates a motif associated with CCR5 binding and its camouflaging glycans

by Sok, Devin, Pauthner, Matthias, Briney, Bryan, Lee, Jeong Hyun, Saye-Francisco, Karen L., Hsueh, Jessica, Ramos, Alejandra, Le, Khoa M., Jones, Meaghan, Jardine, Joseph G., Bastidas, Raiza, Sarkar, Anita, Liang, Chi-Hui, Shivatare, Sachin S., Wu, Chung-Yi, Schief, William R., Wong, Chi-Huey, Wilson, Ian A., Ward, Andrew B., Zhu, Jiang, Poignard, Pascal, Burton, Dennis R.
Published in Immunity (2016)