Antibody engineering & therapeutics, the annual meeting of the antibody society December 7–10, 2015, San Diego, CA, USA

Autor Pauthner, Matthias, Yeung, Jenny, Ullman, Chris, Bakker, Joost, Wurch, Thierry, Reichert, Janice M., Lund-Johansen, Fridtjof, Bradbury, Andrew R.M., Carter, Paul J., Melis, Joost P.M.
Vydáno v MAbs (2016)

Global site-specific analysis of glycoprotein N-glycan processing

Autor Cao, Liwei, Diedrich, Jolene K, Ma, Yuanhui, Wang, Nianshuang, Pauthner, Matthias, Park, Sung-Kyu Robin, Delahunty, Claire M, McLellan, Jason S, Burton, Dennis R, Yates, John R, Paulson, James C
Vydáno v Nat Protoc (2018)

Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization

Autor Bianchi, Matteo, Turner, Hannah L., Nogal, Bartek, Cottrell, Christopher A., Oyen, David, Pauthner, Matthias, Bastidas, Raiza, Nedellec, Rebecca, McCoy, Laura E., Wilson, Ian A., Burton, Dennis R., Ward, Andrew B., Hangartner, Lars
Vydáno v Immunity (2018)

Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques

Autor Zhao, Fangzhu, Joyce, Collin, Burns, Alison, Nogal, Bartek, Cottrell, Christopher A., Ramos, Alejandra, Biddle, Trevor, Pauthner, Matthias, Nedellec, Rebecca, Qureshi, Huma, Mason, Rosemarie, Landais, Elise, Briney, Bryan, Ward, Andrew B., Burton, Dennis R., Sok, Devin
Vydáno v Cell Rep (2020)

Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers

Autor Carnathan, Diane G., Kaushik, Kirti, Ellebedy, Ali H., Enemuo, Chiamaka A., Gebru, Etse H., Dhadvai, Pallavi, Rasheed, Mohammed Ata Ur, Pauthner, Matthias G., Ozorowski, Gabriel, Ahmed, Rafi, Burton, Dennis R., Ward, Andrew B., Silvestri, Guido, Crotty, Shane, Locci, Michela
Vydáno v Front Immunol (2020)

Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen

Autor Jardine, Joseph G., Ota, Takayuki, Sok, Devin, Pauthner, Matthias, Kulp, Daniel W., Kalyuzhniy, Oleksandr, Skog, Patrick D., Thinnes, Theresa C., Bhullar, Deepika, Briney, Bryan, Menis, Sergey, Jones, Meaghan, Kubitz, Mike, Spencer, Skye, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Nemazee, David
Vydáno v Science (2015)

HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite

Autor Nogal, Bartek, McCoy, Laura E., van Gils, Marit J., Cottrell, Christopher A., Voss, James E., Andrabi, Raiees, Pauthner, Matthias, Liang, Chi-Hui, Messmer, Terrence, Nedellec, Rebecca, Shin, Mia, Turner, Hannah L., Ozorowski, Gabriel, Sanders, Rogier W., Burton, Dennis R., Ward, Andrew B.
Vydáno v Sci Adv (2020)

Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits

Autor Yang, Yuhe R., McCoy, Laura E., van Gils, Marit J., Andrabi, Raiees, Turner, Hannah L., Yuan, Meng, Cottrell, Christopher A., Ozorowski, Gabriel, Voss, James, Pauthner, Matthias, Polveroni, Thomas M., Messmer, Terrence, Wilson, Ian A., Sanders, Rogier W., Burton, Dennis R., Ward, Andrew B.
Vydáno v J Virol (2020)

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

Autor Sok, Devin, van Gils, Marit J., Pauthner, Matthias, Julien, Jean-Philippe, Saye-Francisco, Karen L., Hsueh, Jessica, Briney, Bryan, Lee, Jeong Hyun, Le, Khoa M., Lee, Peter S., Hua, Yuanzi, Seaman, Michael S., Moore, John P., Ward, Andrew B., Wilson, Ian A., Sanders, Rogier W., Burton, Dennis R.
Vydáno v Proc Natl Acad Sci U S A (2014)

A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

Autor Lee, Jeong Hyun, Andrabi, Raiees, Su, Ching-Yao, Yasmeen, Anila, Julien, Jean-Philippe, Kong, Leopold, Wu, Nicholas C., McBride, Ryan, Sok, Devin, Pauthner, Matthias, Cottrell, Christopher A., Nieusma, Travis, Blattner, Claudia, Paulson, James C., Klasse, Per Johan, Wilson, Ian A., Burton, Dennis R., Ward, Andrew B.
Vydáno v Immunity (2017)

Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

Autor Sok, Devin, Briney, Bryan, Jardine, Joseph G., Kulp, Daniel W., Menis, Sergey, Pauthner, Matthias, Wood, Andrew, Lee, E-Chiang, Le, Khoa M., Jones, Meaghan, Ramos, Alejandra, Kalyuzhniy, Oleksandr, Adachi, Yumiko, Kubitz, Michael, MacPherson, Skye, Bradley, Allan, Friedrich, Glenn A., Schief, William R., Burton, Dennis R.
Vydáno v Science (2016)

Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer

Autor Cao, Liwei, Pauthner, Matthias, Andrabi, Raiees, Rantalainen, Kimmo, Berndsen, Zachary, Diedrich, Jolene K., Menis, Sergey, Sok, Devin, Bastidas, Raiza, Park, Sung-Kyu Robin, Delahunty, Claire M., He, Lin, Guenaga, Javier, Wyatt, Richard T., Schief, William R., Ward, Andrew B., Yates, John R., Burton, Dennis R., Paulson, James C.
Vydáno v Nat Commun (2018)

Rectal Acquisition of Simian Immunodeficiency Virus (SIV) SIVmac239 Infection despite Vaccine-Induced Immune Responses against the Entire SIV Proteome

Autor Martins, Mauricio A., Gonzalez-Nieto, Lucas, Ricciardi, Michael J., Bailey, Varian K., Dang, Christine M., Bischof, Georg F., Pedreño-Lopez, Nuria, Pauthner, Matthias G., Burton, Dennis R., Parks, Christopher L., Earl, Patricia, Moss, Bernard, Rakasz, Eva G., Lifson, Jeffrey D., Desrosiers, Ronald C., Watkins, David I.
Vydáno v J Virol (2020)

Global site-specific N-glycosylation analysis of HIV envelope glycoprotein

Autor Cao, Liwei, Diedrich, Jolene K., Kulp, Daniel W., Pauthner, Matthias, He, Lin, Park, Sung-Kyu Robin, Sok, Devin, Su, Ching Yao, Delahunty, Claire M., Menis, Sergey, Andrabi, Raiees, Guenaga, Javier, Georgeson, Erik, Kubitz, Michael, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Yates III, John R., Paulson, James C.
Vydáno v Nat Commun (2017)

The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template

Autor Andrabi, Raiees, Pallesen, Jesper, Allen, Joel D., Song, Ge, Zhang, Jinsong, de Val, Natalia, Gegg, Gavin, Porter, Katelyn, Su, Ching-Yao, Pauthner, Matthias, Newman, Amanda, Bouton-Verville, Hilary, Garces, Fernando, Wilson, Ian A., Crispin, Max, Hahn, Beatrice H., Haynes, Barton F., Verkoczy, Laurent, Ward, Andrew B., Burton, Dennis R.
Vydáno v Cell Rep (2019)

Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies

Autor McCoy, Laura E, van Gils, Marit J, Ozorowski, Gabriel, Messmer, Terrence, Briney, Bryan, Voss, James E, Kulp, Daniel W, Macauley, Matthew S, Sok, Devin, Pauthner, Matthias, Menis, Sergey, Cottrell, Christopher A, Torres, Jonathan L, Hsueh, Jessica, Schief, William R, Wilson, Ian A, Ward, Andrew B, Sanders, Rogier W, Burton, Dennis R
Vydáno v Cell Rep (2016)

Infection of Monkeys by Simian-human Immunodeficiency Viruses with Transmitted/ founder Clade C HIV-1 Envelopes

Autor Asmal, Mohammed, Luedemann, Corinne, Lavine, Christy L., Mach, Linh V., Balachandran, Harikrishnan, Brinkley, Christie, Denny, Thomas N., Lewis, Mark G., Anderson, Hanne, Pal, Ranajit, Sok, Devin, Le, Khoa, Pauthner, Matthias, Hahn, Beatrice H., Shaw, George M., Seaman, Michael S., Letvin, Norman L., Burton, Dennis R., Sodroski, Joseph G., Haynes, Barton F., Santra, Sampa
Vydáno v Virology (2014)

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

Autor Kulp, Daniel W., Steichen, Jon M., Pauthner, Matthias, Hu, Xiaozhen, Schiffner, Torben, Liguori, Alessia, Cottrell, Christopher A., Havenar-Daughton, Colin, Ozorowski, Gabriel, Georgeson, Erik, Kalyuzhniy, Oleksandr, Willis, Jordan R., Kubitz, Michael, Adachi, Yumiko, Reiss, Samantha M., Shin, Mia, de Val, Natalia, Ward, Andrew B., Crotty, Shane, Burton, Dennis R., Schief, William R.
Vydáno v Nat Commun (2017)

A meta-analysis of passive immunization studies shows an association of serum neutralizing antibody titer with protection against SHIV challenge

Autor Pegu, Amarendra, Borate, Bhavesh, Huang, Yunda, Pauthner, Matthias G., Hessell, Ann J., Julg, Boris, Doria-Rose, Nicole A., Schmidt, Stephen D., Carpp, Lindsay N., Cully, Michelle D., Chen, Xuejun, Shaw, George M., Barouch, Dan H., Haigwood, Nancy L., Corey, Lawrence, Burton, Dennis R., Roederer, Mario, Gilbert, Peter B., Mascola, John R., Huang, Ying
Vydáno v Cell Host Microbe (2019)

A prominent site of antibody vulnerability on HIV envelope incorporates a motif associated with CCR5 binding and its camouflaging glycans

Autor Sok, Devin, Pauthner, Matthias, Briney, Bryan, Lee, Jeong Hyun, Saye-Francisco, Karen L., Hsueh, Jessica, Ramos, Alejandra, Le, Khoa M., Jones, Meaghan, Jardine, Joseph G., Bastidas, Raiza, Sarkar, Anita, Liang, Chi-Hui, Shivatare, Sachin S., Wu, Chung-Yi, Schief, William R., Wong, Chi-Huey, Wilson, Ian A., Ward, Andrew B., Zhu, Jiang, Poignard, Pascal, Burton, Dennis R.
Vydáno v Immunity (2016)