Antibody engineering & therapeutics, the annual meeting of the antibody society December 7–10, 2015, San Diego, CA, USA

per Pauthner, Matthias, Yeung, Jenny, Ullman, Chris, Bakker, Joost, Wurch, Thierry, Reichert, Janice M., Lund-Johansen, Fridtjof, Bradbury, Andrew R.M., Carter, Paul J., Melis, Joost P.M.
Publicat a MAbs (2016)

Global site-specific analysis of glycoprotein N-glycan processing

per Cao, Liwei, Diedrich, Jolene K, Ma, Yuanhui, Wang, Nianshuang, Pauthner, Matthias, Park, Sung-Kyu Robin, Delahunty, Claire M, McLellan, Jason S, Burton, Dennis R, Yates, John R, Paulson, James C
Publicat a Nat Protoc (2018)

Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization

per Bianchi, Matteo, Turner, Hannah L., Nogal, Bartek, Cottrell, Christopher A., Oyen, David, Pauthner, Matthias, Bastidas, Raiza, Nedellec, Rebecca, McCoy, Laura E., Wilson, Ian A., Burton, Dennis R., Ward, Andrew B., Hangartner, Lars
Publicat a Immunity (2018)

Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques

per Zhao, Fangzhu, Joyce, Collin, Burns, Alison, Nogal, Bartek, Cottrell, Christopher A., Ramos, Alejandra, Biddle, Trevor, Pauthner, Matthias, Nedellec, Rebecca, Qureshi, Huma, Mason, Rosemarie, Landais, Elise, Briney, Bryan, Ward, Andrew B., Burton, Dennis R., Sok, Devin
Publicat a Cell Rep (2020)

Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers

per Carnathan, Diane G., Kaushik, Kirti, Ellebedy, Ali H., Enemuo, Chiamaka A., Gebru, Etse H., Dhadvai, Pallavi, Rasheed, Mohammed Ata Ur, Pauthner, Matthias G., Ozorowski, Gabriel, Ahmed, Rafi, Burton, Dennis R., Ward, Andrew B., Silvestri, Guido, Crotty, Shane, Locci, Michela
Publicat a Front Immunol (2020)

Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen

per Jardine, Joseph G., Ota, Takayuki, Sok, Devin, Pauthner, Matthias, Kulp, Daniel W., Kalyuzhniy, Oleksandr, Skog, Patrick D., Thinnes, Theresa C., Bhullar, Deepika, Briney, Bryan, Menis, Sergey, Jones, Meaghan, Kubitz, Mike, Spencer, Skye, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Nemazee, David
Publicat a Science (2015)

HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite

per Nogal, Bartek, McCoy, Laura E., van Gils, Marit J., Cottrell, Christopher A., Voss, James E., Andrabi, Raiees, Pauthner, Matthias, Liang, Chi-Hui, Messmer, Terrence, Nedellec, Rebecca, Shin, Mia, Turner, Hannah L., Ozorowski, Gabriel, Sanders, Rogier W., Burton, Dennis R., Ward, Andrew B.
Publicat a Sci Adv (2020)

Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits

per Yang, Yuhe R., McCoy, Laura E., van Gils, Marit J., Andrabi, Raiees, Turner, Hannah L., Yuan, Meng, Cottrell, Christopher A., Ozorowski, Gabriel, Voss, James, Pauthner, Matthias, Polveroni, Thomas M., Messmer, Terrence, Wilson, Ian A., Sanders, Rogier W., Burton, Dennis R., Ward, Andrew B.
Publicat a J Virol (2020)

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

per Sok, Devin, van Gils, Marit J., Pauthner, Matthias, Julien, Jean-Philippe, Saye-Francisco, Karen L., Hsueh, Jessica, Briney, Bryan, Lee, Jeong Hyun, Le, Khoa M., Lee, Peter S., Hua, Yuanzi, Seaman, Michael S., Moore, John P., Ward, Andrew B., Wilson, Ian A., Sanders, Rogier W., Burton, Dennis R.
Publicat a Proc Natl Acad Sci U S A (2014)

A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

per Lee, Jeong Hyun, Andrabi, Raiees, Su, Ching-Yao, Yasmeen, Anila, Julien, Jean-Philippe, Kong, Leopold, Wu, Nicholas C., McBride, Ryan, Sok, Devin, Pauthner, Matthias, Cottrell, Christopher A., Nieusma, Travis, Blattner, Claudia, Paulson, James C., Klasse, Per Johan, Wilson, Ian A., Burton, Dennis R., Ward, Andrew B.
Publicat a Immunity (2017)

Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

per Sok, Devin, Briney, Bryan, Jardine, Joseph G., Kulp, Daniel W., Menis, Sergey, Pauthner, Matthias, Wood, Andrew, Lee, E-Chiang, Le, Khoa M., Jones, Meaghan, Ramos, Alejandra, Kalyuzhniy, Oleksandr, Adachi, Yumiko, Kubitz, Michael, MacPherson, Skye, Bradley, Allan, Friedrich, Glenn A., Schief, William R., Burton, Dennis R.
Publicat a Science (2016)

Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer

per Cao, Liwei, Pauthner, Matthias, Andrabi, Raiees, Rantalainen, Kimmo, Berndsen, Zachary, Diedrich, Jolene K., Menis, Sergey, Sok, Devin, Bastidas, Raiza, Park, Sung-Kyu Robin, Delahunty, Claire M., He, Lin, Guenaga, Javier, Wyatt, Richard T., Schief, William R., Ward, Andrew B., Yates, John R., Burton, Dennis R., Paulson, James C.
Publicat a Nat Commun (2018)

Rectal Acquisition of Simian Immunodeficiency Virus (SIV) SIVmac239 Infection despite Vaccine-Induced Immune Responses against the Entire SIV Proteome

per Martins, Mauricio A., Gonzalez-Nieto, Lucas, Ricciardi, Michael J., Bailey, Varian K., Dang, Christine M., Bischof, Georg F., Pedreño-Lopez, Nuria, Pauthner, Matthias G., Burton, Dennis R., Parks, Christopher L., Earl, Patricia, Moss, Bernard, Rakasz, Eva G., Lifson, Jeffrey D., Desrosiers, Ronald C., Watkins, David I.
Publicat a J Virol (2020)

Global site-specific N-glycosylation analysis of HIV envelope glycoprotein

per Cao, Liwei, Diedrich, Jolene K., Kulp, Daniel W., Pauthner, Matthias, He, Lin, Park, Sung-Kyu Robin, Sok, Devin, Su, Ching Yao, Delahunty, Claire M., Menis, Sergey, Andrabi, Raiees, Guenaga, Javier, Georgeson, Erik, Kubitz, Michael, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Yates III, John R., Paulson, James C.
Publicat a Nat Commun (2017)

The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template

per Andrabi, Raiees, Pallesen, Jesper, Allen, Joel D., Song, Ge, Zhang, Jinsong, de Val, Natalia, Gegg, Gavin, Porter, Katelyn, Su, Ching-Yao, Pauthner, Matthias, Newman, Amanda, Bouton-Verville, Hilary, Garces, Fernando, Wilson, Ian A., Crispin, Max, Hahn, Beatrice H., Haynes, Barton F., Verkoczy, Laurent, Ward, Andrew B., Burton, Dennis R.
Publicat a Cell Rep (2019)

Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies

per McCoy, Laura E, van Gils, Marit J, Ozorowski, Gabriel, Messmer, Terrence, Briney, Bryan, Voss, James E, Kulp, Daniel W, Macauley, Matthew S, Sok, Devin, Pauthner, Matthias, Menis, Sergey, Cottrell, Christopher A, Torres, Jonathan L, Hsueh, Jessica, Schief, William R, Wilson, Ian A, Ward, Andrew B, Sanders, Rogier W, Burton, Dennis R
Publicat a Cell Rep (2016)

Infection of Monkeys by Simian-human Immunodeficiency Viruses with Transmitted/ founder Clade C HIV-1 Envelopes

per Asmal, Mohammed, Luedemann, Corinne, Lavine, Christy L., Mach, Linh V., Balachandran, Harikrishnan, Brinkley, Christie, Denny, Thomas N., Lewis, Mark G., Anderson, Hanne, Pal, Ranajit, Sok, Devin, Le, Khoa, Pauthner, Matthias, Hahn, Beatrice H., Shaw, George M., Seaman, Michael S., Letvin, Norman L., Burton, Dennis R., Sodroski, Joseph G., Haynes, Barton F., Santra, Sampa
Publicat a Virology (2014)

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

per Kulp, Daniel W., Steichen, Jon M., Pauthner, Matthias, Hu, Xiaozhen, Schiffner, Torben, Liguori, Alessia, Cottrell, Christopher A., Havenar-Daughton, Colin, Ozorowski, Gabriel, Georgeson, Erik, Kalyuzhniy, Oleksandr, Willis, Jordan R., Kubitz, Michael, Adachi, Yumiko, Reiss, Samantha M., Shin, Mia, de Val, Natalia, Ward, Andrew B., Crotty, Shane, Burton, Dennis R., Schief, William R.
Publicat a Nat Commun (2017)

A meta-analysis of passive immunization studies shows an association of serum neutralizing antibody titer with protection against SHIV challenge

per Pegu, Amarendra, Borate, Bhavesh, Huang, Yunda, Pauthner, Matthias G., Hessell, Ann J., Julg, Boris, Doria-Rose, Nicole A., Schmidt, Stephen D., Carpp, Lindsay N., Cully, Michelle D., Chen, Xuejun, Shaw, George M., Barouch, Dan H., Haigwood, Nancy L., Corey, Lawrence, Burton, Dennis R., Roederer, Mario, Gilbert, Peter B., Mascola, John R., Huang, Ying
Publicat a Cell Host Microbe (2019)

A prominent site of antibody vulnerability on HIV envelope incorporates a motif associated with CCR5 binding and its camouflaging glycans

per Sok, Devin, Pauthner, Matthias, Briney, Bryan, Lee, Jeong Hyun, Saye-Francisco, Karen L., Hsueh, Jessica, Ramos, Alejandra, Le, Khoa M., Jones, Meaghan, Jardine, Joseph G., Bastidas, Raiza, Sarkar, Anita, Liang, Chi-Hui, Shivatare, Sachin S., Wu, Chung-Yi, Schief, William R., Wong, Chi-Huey, Wilson, Ian A., Ward, Andrew B., Zhu, Jiang, Poignard, Pascal, Burton, Dennis R.
Publicat a Immunity (2016)