Studies for the enantiocontrolled preparation of substituted tetrahydropyrans: Applications for the synthesis of leucascandrolide A macrolactone

Autor Williams, David R., Plummer, Scott V., Patnaik, Samarjit
Vydáno 2011

Progress and potential of non-inhibitory small molecule chaperones for the treatment of Gaucher disease and its potential implications for Parkinson disease

Autor Jung, Olive, Patnaik, Samarjit, Marugan, Juan, Sidransky, Ellen, Westbroek, Wendy
Vydáno v Expert Rev Proteomics (2016)

Multi-Gram Scale Synthesis of FR180204

Autor Patnaik, Samarjit, Dietz, Harry C., Zheng, Wei, Austin, Christopher, Marugan, Juan J.
Vydáno 2009

Ligand-Induced GPR110 Activation Facilitates Axon Growth after Injury

Autor Kwon, Heungsun, Kevala, Karl, Xin, Hu, Patnaik, Samarjit, Marugan, Juan, Kim, Hee-Yong
Vydáno v Int J Mol Sci (2021)

Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19

Autor Eastman, Richard T., Roth, Jacob S., Brimacombe, Kyle R., Simeonov, Anton, Shen, Min, Patnaik, Samarjit, Hall, Matthew D.
Vydáno v ACS Cent Sci (2020)

Correction to Remdesivir: A Review of Its Discovery and Development Leading to Human Clinical Trials for Treatment of COVID-19

Autor Eastman, Richard T., Roth, Jacob S., Brimacombe, Kyle R., Simeonov, Anton, Shen, Min, Patnaik, Samarjit, Hall, Matthew D.
Vydáno v ACS Cent Sci (2020)

Identification of activators of human fumarate hydratase by quantitative high-throughput screening

Autor Zhu, Hu, Lee, Olivia W., Shah, Pranav, Jadhav, Ajit, Xu, Xin, Patnaik, Samarjit, Shen, Min, Hall, Matthew D.
Vydáno v SLAS Discov (2019)

Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function

Autor Lee, Ji-Won, Huang, Bill X., Kwon, HeungSun, Rashid, Md Abdur, Kharebava, Giorgi, Desai, Abhishek, Patnaik, Samarjit, Marugan, Juan, Kim, Hee-Yong
Vydáno v Nat Commun (2016)

Identification of 4-phenylquinolin-2(1H)-one as a specific allosteric inhibitor of Akt

Autor Huang, Bill X., Newcomer, Kenny, Kevala, Karl, Barnaeva, Elena, Zheng, Wei, Hu, Xin, Patnaik, Samarjit, Southall, Noel, Marugan, Juan, Ferrer, Marc, Kim, Hee-Yong
Vydáno v Sci Rep (2017)

Lysosomal storage and impaired autophagy lead to inflammasome activation in Gaucher macrophages

Autor Aflaki, Elma, Moaven, Nima, Borger, Daniel K., Lopez, Grisel, Westbroek, Wendy, Chae, Jae Jin, Marugan, Juan, Patnaik, Samarjit, Maniwang, Emerson, Gonzalez, Ashley N., Sidransky, Ellen
Vydáno v Aging Cell (2015)

Discovery, SAR, and Biological evaluation of Non-Inhibitory Small Molecule Chaperones of Glucocerebrosidase

Autor Patnaik, Samarjit, Zheng, Wei, Choi, Jae H., Motabar, Omid, Southall, Noel, Westbroek, Wendy, Lea, Wendy A., Velayati, Arash, Goldin, Ehud, Sidransky, Ellen, Leister, William, Marugan, Juan J.
Vydáno 2012

Macrophage Models of Gaucher Disease for Evaluating Disease Pathogenesis and Candidate Drugs

Autor Aflaki, Elma, Stubblefield, Barbara K., Maniwang, Emerson, Lopez, Grisel, Moaven, Nima, Goldin, Ehud, Marugan, Juan, Patnaik, Samarjit, Dutra, Amalia, Southall, Noel, Zheng, Wei, Tayebi, Nahid, Sidransky, Ellen
Vydáno 2014

Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons

Autor Mazzulli, Joseph R., Zunke, Friederike, Tsunemi, Taiji, Toker, Nicholas J., Jeon, Sohee, Burbulla, Lena F., Patnaik, Samarjit, Sidransky, Ellen, Marugan, Juan J., Sue, Carolyn M., Krainc, Dimitri
Vydáno v J Neurosci (2016)

MCOLN1 is a ROS sensor in lysosomes that regulates autophagy

Autor Zhang, Xiaoli, Cheng, Xiping, Yu, Lu, Yang, Junsheng, Calvo, Raul, Patnaik, Samarjit, Hu, Xin, Gao, Qiong, Yang, Meimei, Lawas, Maria, Delling, Markus, Marugan, Juan, Ferrer, Marc, Xu, Haoxing
Vydáno v Nat Commun (2016)

Non-iminosugar glucocerebrosidase small molecule chaperones

Autor Marugan, Juan Jose, Huang, Wenwei, Motabar, Omid, Zheng, Wei, Xiao, Jingbo, Patnaik, Samarjit, Southall, Noel, Westbroek, Wendy, Lea, Wendy A., Simeonov, Anton, Goldin, Ehud, DeBernardi, Maria A., Sidransky, Ellen
Vydáno 2011

Structure Activity Relationship of Imidazo-pyridinium Analogs as Antagonists of Neuropeptide S Receptor

Autor Patnaik, Samarjit, Marugan, Juan J., Liu, Ke, Zheng, Wei, Southall, Noel, Dehdashti, Seameen J., Thorsell, Annika, Heilig, Markus, Bell, Lauren, Zook, Michelle, Eskay, Bob, Brimacombe, Kyle R., Austin, Christopher P.
Vydáno v J Med Chem (2013)

Metabolism and PK characterization of metarrestin in multiple species

Autor Padilha, Elias C., Shah, Pranav, Wang, Amy Q., Singleton, Marc D., Hughes, Emma A., Li, Dandan, Rice, Kelly A., Konrath, Kylie M., Patnaik, Samarjit, Marugan, Juan, Rudloff, Udo, Xu, Xin
Vydáno v Cancer Chemother Pharmacol (2020)

Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells

Autor Singh, Anju, Dashynam, Myagmarjav, Chim, Bryan, Escobar, Thelma M., Liu, Xiuhuai, Hu, Xin, Patnaik, Samarjit, Xu, Xin, Southall, Noel, Marugan, Juan, Jadhav, Ajit, Lazarevic, Vanja, Muljo, Stefan A., Ferrer, Marc
Vydáno v Sci Rep (2021)

Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects

Autor Hoskins, Jason W., Ofori, Leslie O., Chen, Catherine Z., Kumar, Amit, Sobczak, Krzysztof, Nakamori, Masayuki, Southall, Noel, Patnaik, Samarjit, Marugan, Juan J., Zheng, Wei, Austin, Christopher P., Disney, Matthew D., Miller, Benjamin L., Thornton, Charles A.
Vydáno 2014

A Novel Brain Penetrant NPS Receptor Antagonist, NCGC00185684, Blocks Alcohol-Induced ERK-Phosphorylation in the Central Amygdala and Decreases Operant Alcohol Self-Administration...

Autor Thorsell, Annika, Tapocik, Jenica D., Liu, Ke, Zook, Michelle, Bell, Lauren, Flanigan, Meghan, Patnaik, Samarjit, Marugan, Juan, Damadzic, Ruslan, Dehdashti, Seameen J., Schwandt, Melanie L., Southall, Noel, Austin, Christopher P., Eskay, Robert, Ciccocioppo, Roberto, Zheng, Wei, Heilig, Markus
Vydáno 2013