Trisubstituted (E)-Alkene Dipeptide Isosteres as β-Turn Promoters in the Gramicidin S Cyclodecapeptide Scaffold

Por Xiao, Jingbo, Weisblum, Bernard, Wipf, Peter
Publicado em 2006

Peptide-Like Molecules (PLMs): A Journey from Peptide Bond Isosteres to Gramicidin S Mimetics and Mitochondrial Targeting Agents

Por Wipf, Peter, Xiao, Jingbo, Stephenson, Corey R. J.
Publicado em 2009

High relapse rate and poor medication adherence in the Chinese population with schizophrenia: results from an observational survey in the People’s Republic of China

Por Xiao, Jingbo, Mi, Weifeng, Li, Lingzhi, Shi, Ying, Zhang, Hongyan
Publicado no Neuropsychiatr Dis Treat (2015)

Mitochondrial targeting of radioprotectants using peptidyl conjugates

Por Kanai, Anthony, Zabbarova, Irina, Amoscato, Andrew, Epperly, Michael, Xiao, Jingbo, Wipf, Peter
Publicado em 2006

Plasma and Tissue Concentrations of α-Tocopherol and δ-Tocopherol Following High Dose Dietary Supplementation in Mice

Por Baxter, Laura L., Marugan, Juan J., Xiao, Jingbo, Incao, Art, McKew, John C., Zheng, Wei, Pavan, William J.
Publicado em 2012

A Selective TSH Receptor Antagonist Inhibits Stimulation of Thyroid Function in Female Mice

Por Neumann, Susanne, Nir, Eshel A., Eliseeva, Elena, Huang, Wenwei, Marugan, Juan, Xiao, Jingbo, Dulcey, Andrés E., Gershengorn, Marvin C.
Publicado em 2014

Discovery, Synthesis and Biological Evaluation of Novel SMN Protein Modulators

Por Xiao, Jingbo, Marugan, Juan J., Zheng, Wei, Titus, Steve, Southall, Noel, Cherry, Jonathan J., Evans, Matthew, Androphy, Elliot J., Austin, Christopher P.
Publicado em 2011

Use of transcriptional synergy to augment sensitivity of a splicing reporter assay

Por Levinson, Noah, Hinman, Rochelle, Patil, Ashwini, Stephenson, Corey R.J., Werner, Stefan, Woo, Grace H.C., Xiao, Jingbo, Wipf, Peter, Lynch, Kristen W.
Publicado em 2006

Treatment With a Novel Hemigramicidin-TEMPO Conjugate Prolongs Survival in a Rat Model of Lethal Hemorrhagic Shock

Por Macias, Carlos A., Chiao, Jeffrey W., Xiao, Jingbo, Arora, Devinder S., Tyurina, Yulia Y., Delude, Russell L., Wipf, Peter, Kagan, Valerian E., Fink, Mitchell P.
Publicado em 2007

Structural insights into the activation of human relaxin family peptide receptor 1 by small molecule agonists

Por Hu, Xin, Myhr, Courtney, Huang, Zaohua, Xiao, Jingbo, Barnaeva, Elena, Ho, Brian A., Agoulnik, Irina U., Ferrer, Marc, Marugan, Juan J., Southall, Noel, Agoulnik, Alexander I.
Publicado no Biochemistry (2016)

Identification of small molecule agonists of human relaxin family receptor 1 (RXFP1) by utilizing a homogenous cell-based cAMP assay

Por Chen, Catherine Z., Southall, Noel, Xiao, Jingbo, Marugan, Juan J., Ferrer, Marc, Hu, Xin, Jones, Raisa E., Feng, Shu, Agoulnik, Irina U., Zheng, Wei, Agoulnik, Alexander I.
Publicado no J Biomol Screen (2012)

Identification and optimization of small-molecule agonists of the human relaxin hormone receptor RXFP1

Por Xiao, Jingbo, Huang, Zaohua, Chen, Catherine Z., Agoulnik, Irina U., Southall, Noel, Hu, Xin, Jones, Raisa E., Ferrer, Marc, Zheng, Wei, Agoulnik, Alexander I., Marugan, Juan J.
Publicado no Nat Commun (2013)

Non-iminosugar glucocerebrosidase small molecule chaperones

Por Marugan, Juan Jose, Huang, Wenwei, Motabar, Omid, Zheng, Wei, Xiao, Jingbo, Patnaik, Samarjit, Southall, Noel, Westbroek, Wendy, Lea, Wendy A., Simeonov, Anton, Goldin, Ehud, DeBernardi, Maria A., Sidransky, Ellen
Publicado em 2011

Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection

Por He, Shanshan, Xiao, Jingbo, Dulcey, Andrés E., Lin, Billy, Rolt, Adam, Hu, Zongyi, Hu, Xin, Wang, Amy Q., Xu, Xin, Southall, Noel, Ferrer, Marc, Zheng, Wei, Liang, T. Jake, Marugan, Juan J.
Publicado no J Med Chem (2015)

Activation of Relaxin Family Receptor 1 from Different Mammalian Species by Relaxin Peptide and Small-Molecule Agonist ML290

Por Huang, Zaohua, Myhr, Courtney, Bathgate, Ross A. D., Ho, Brian A., Bueno, Amaya, Hu, Xin, Xiao, Jingbo, Southall, Noel, Barnaeva, Elena, Agoulnik, Irina U., Marugan, Juan J., Ferrer, Marc, Agoulnik, Alexander I.
Publicado no Front Endocrinol (Lausanne) (2015)

Identification of Novel Anti-Hepatitis C Virus Agents by a Quantitative High Throughput Screen in a Cell-Based Infection Assay

Por Hu, Zongyi, Hu, Xin, He, Shanshan, Yim, Hyung Joon, Xiao, Jingbo, Swaroop, Manju, Tanega, Cordelle, Zhang, Ya-qin, Yi, Guanghui, Kao, C. Cheng, Marugan, Juan, Ferrer, Marc, Zheng, Wei, Southall, Noel, Liang, T. Jake
Publicado no Antiviral Res (2015)

Discovery, Optimization, and Characterization of Novel D(2) Dopamine Receptor Selective Antagonists

Por Xiao, Jingbo, Free, R. Benjamin, Barnaeva, Elena, Conroy, Jennie L., Doyle, Trevor, Miller, Brittney, Bryant-Genevier, Marthe, Taylor, Mercedes K., Hu, Xin, Dulcey, Andrés E., Southall, Noel, Ferrer, Marc, Titus, Steve, Zheng, Wei, Sibley, David R., Marugan, Juan J.
Publicado no J Med Chem (2014)

ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice

Por Abera, Mahlet B., Xiao, Jingbo, Nofziger, Jonathan, Titus, Steve, Southall, Noel, Zheng, Wei, Moritz, Kasey E., Ferrer, Marc, Cherry, Jonathan J., Androphy, Elliot J., Wang, Amy, Xu, Xin, Austin, Christopher, Fischbeck, Kenneth H., Marugan, Juan J., Burnett, Barrington G.
Publicado no JCI Insight (2016)

Discovery of a novel non-iminosugar acid alpha glucosidase chaperone series

Por Xiao, Jingbo, Westbroek, Wendy, Motabar, Omid, Lea, Wendy A., Hu, Xin, Velayati, Arash, Zheng, Wei, Southall, Noel, Gustafson, Ann Marie, Goldin, Ehud, Sidransky, Ellen, Liu, Ke, Simeonov, Anton, Tamargo, Rafael J., Ribes, Antonia, Matalonga, Leslie, Ferrer, Marc, Marugan, Juan J.
Publicado em 2012

δ-Tocopherol Reduces Lipid Accumulation in Niemann-Pick Type C1 and Wolman Cholesterol Storage Disorders

Por Xu, Miao, Liu, Ke, Swaroop, Manju, Porter, Forbes D., Sidhu, Rohini, Finkes, Sally, Ory, Daniel S., Marugan, Juan J., Xiao, Jingbo, Southall, Noel, Pavan, William J., Davidson, Cristin, Walkley, Steven U., Remaley, Alan T., Baxa, Ulrich, Sun, Wei, McKew, John C., Austin, Christopher P., Zheng, Wei
Publicado em 2012