A carregar...
Trisubstituted (E)-Alkene Dipeptide Isosteres as β-Turn Promoters in the Gramicidin S Cyclodecapeptide Scaffold
A concise synthesis of a gramicidin S analogue with trisubstituted (E)-alkene dipeptide isostere (TEADI) replacements at both (D)Phe-Pro positions was realized. Conformational analysis demonstrated that TEADIs can serve as type II β-turn promoters in a cyclic scaffold and successfully mimic a prolin...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631548/ https://ncbi.nlm.nih.gov/pubmed/17020289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol0617704 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|