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Diastereoselective Coupling of Chiral Acetonide Trisubstituted Radicals with Alkenes

The stereochemical outcome of reactions of chiral nucleophilic trisubstituted acetonide radicals with electron-deficient alkenes is dictated by a delicate balance between destabilizing non-bonding interactions and stabilizing hydrogen-bonding between substituents on the α and β carbons.

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Dades bibliogràfiques
Publicat a:Chemistry
Autors principals: Tao, Daniel J., Muuronen, Mikko, Slutskyy, Yuriy, Le, Alexander, Furche, Filipp, Overman, Larry E.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978530/
https://ncbi.nlm.nih.gov/pubmed/27128888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201601957
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