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Allylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide Isosteres

Nucleophilic imine additions with vinyl organometallics have developed into efficient, high yielding, and robust methodologies to generate structurally diverse allylic amines. We have used the hydrozirconation-transmetalation-imine addition protocol in the synthesis of allylic amine intermediates fo...

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Autori principali: Skoda, Erin M., Davis, Gary C., Wipf, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272643/
https://ncbi.nlm.nih.gov/pubmed/22323894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/op2002613
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