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Use of transcriptional synergy to augment sensitivity of a splicing reporter assay
A primary limitation in the development and use of screens to identify factors that regulate mammalian pre-mRNA splicing has been the development of sensitive reporter assays. Alternative splicing typically involves relatively small (< 10-fold) changes in isoform ratios. Therefore, reporter const...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440914/ https://ncbi.nlm.nih.gov/pubmed/16556940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.8306 |
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