A Small Molecule Inverse Agonist for the Human Thyroid-Stimulating Hormone Receptor

بواسطة Neumann, Susanne, Huang, Wenwei, Eliseeva, Elena, Titus, Steve, Thomas, Craig J., Gershengorn, Marvin C.
منشور في 2010

Comparison on Functional Assays for Gq-Coupled GPCRs by Measuring Inositol Monophospate-1 and Intracellular Calcium in 1536-Well Plate Format

بواسطة Liu, Ke, Titus, Steve, Southall, Noel, Zhu, Pingjun, Inglese, James, Austin, Christopher P, Zheng, Wei
منشور في 2008

Tetracycline-Inducible Gene Expression in Conditionally Immortalized Mouse Podocytes

بواسطة Kajiyama, Hiroshi, Titus, Steve, Austin, Christopher P., Chiotos, Kathleen, Matsumoto, Takayuki, Sakairi, Toru, Kopp, Jeffrey B.
منشور في 2009

One-step seeding of neural stem cells with vitronectin-supplemented medium for high throughput screening assays

بواسطة Dai, Sheng, Li, Rong, Long, Yan, Titus, Steve, Zhao, Jinghua, Huang, Ruili, Xia, Menghang, Zheng, Wei
الحاوية / القاعدة J Biomol Screen (2016)

A Panel of Diverse Assays to Interrogate the Interaction between Glucokinase and Glucokinase Regulatory Protein, Two Vital Proteins in Human Disease

بواسطة Rees, Matthew G., Davis, Mindy I., Shen, Min, Titus, Steve, Raimondo, Anne, Barrett, Amy, Gloyn, Anna L., Collins, Francis S., Simeonov, Anton
منشور في 2014

A Multiplex Calcium Assay for Identification of GPCR Agonists and Antagonists

بواسطة Liu, Ke, Southall, Noel, Titus, Steve A., Inglese, James, Eskay, Robert L., Shinn, Paul, Austin, Christopher P., Heilig, Markus A., Zheng, Wei
منشور في 2010

Discovery, Synthesis and Biological Evaluation of Novel SMN Protein Modulators

بواسطة Xiao, Jingbo, Marugan, Juan J., Zheng, Wei, Titus, Steve, Southall, Noel, Cherry, Jonathan J., Evans, Matthew, Androphy, Elliot J., Austin, Christopher P.
منشور في 2011

Quantitative High Throughput Screening Using a Live Cell cAMP Assay Identifies Small Molecule Agonists of the TSH Receptor

بواسطة Titus, Steve, Neumann, Susanne, Zheng, Wei, Southall, Noel, Michael, Sam, Klumpp, Carleen, Yasgar, Adam, Shinn, Paul, Thomas, Craig J., Inglese, Jim, Gershengorn, Marvin C., Austin, Christopher P.
منشور في 2008

Large-scale pharmacological profiling of 3D tumor models of cancer cells

بواسطة Mathews Griner, Lesley A, Zhang, Xiaohu, Guha, Rajarshi, McKnight, Crystal, Goldlust, Ian S, Lal-Nag, Madhu, Wilson, Kelli, Michael, Sam, Titus, Steve, Shinn, Paul, Thomas, Craig J, Ferrer, Marc
الحاوية / القاعدة Cell Death Dis (2016)

Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice

بواسطة Neumann, Susanne, Huang, Wenwei, Titus, Steve, Krause, Gerd, Kleinau, Gunnar, Alberobello, Anna Teresa, Zheng, Wei, Southall, Noel T., Inglese, James, Austin, Christopher P., Celi, Francesco S., Gavrilova, Oksana, Thomas, Craig J., Raaka, Bruce M., Gershengorn, Marvin C.
منشور في 2009

Discovery, Optimization, and Characterization of Novel D(2) Dopamine Receptor Selective Antagonists

بواسطة Xiao, Jingbo, Free, R. Benjamin, Barnaeva, Elena, Conroy, Jennie L., Doyle, Trevor, Miller, Brittney, Bryant-Genevier, Marthe, Taylor, Mercedes K., Hu, Xin, Dulcey, Andrés E., Southall, Noel, Ferrer, Marc, Titus, Steve, Zheng, Wei, Sibley, David R., Marugan, Juan J.
الحاوية / القاعدة J Med Chem (2014)

ML372 blocks SMN ubiquitination and improves spinal muscular atrophy pathology in mice

بواسطة Abera, Mahlet B., Xiao, Jingbo, Nofziger, Jonathan, Titus, Steve, Southall, Noel, Zheng, Wei, Moritz, Kasey E., Ferrer, Marc, Cherry, Jonathan J., Androphy, Elliot J., Wang, Amy, Xu, Xin, Austin, Christopher, Fischbeck, Kenneth H., Marugan, Juan J., Burnett, Barrington G.
الحاوية / القاعدة JCI Insight (2016)

Identification of Positive Allosteric Modulators of the D(1) Dopamine Receptor That Act at Diverse Binding Sites

بواسطة Luderman, Kathryn D., Conroy, Jennie L., Free, R. Benjamin, Southall, Noel, Ferrer, Marc, Sanchez-Soto, Marta, Moritz, Amy E., Willette, Blair K. A., Fyfe, Tim J., Jain, Prashi, Titus, Steve, Hazelwood, Lisa A., Aubé, Jeffrey, Lane, J. Robert, Frankowski, Kevin J., Sibley, David R.
الحاوية / القاعدة Mol Pharmacol (2018)

A TRP Channel in the Lysosome Regulates Large Particle Phagocytosis via Focal Exocytosis

بواسطة Samie, Mohammad, Wang, Xiang, Zhang, Xiaoli, Goschka, Andrew, Li, Xinran, Cheng, Xiping, Gregg, Evan, Azar, Marlene, Zhuo, Yue, Garrity, Abigail, Gao, Qiong, Slaugenhaupt, Susan, Pickel, Jim, Zolov, Sergey N., Weisman, Lois S., Lenk, Guy M., Titus, Steve, Bryant-Genevier, Marthe, Southall, Noel, Juan, Marugan, Ferrer, Marc, Xu, Haoxing
منشور في 2013

Discovery and Characterization of a G Protein–Biased Agonist That Inhibits β-Arrestin Recruitment to the D2 Dopamine Receptor

بواسطة Free, R. Benjamin, Chun, Lani S., Moritz, Amy E., Miller, Brittney N., Doyle, Trevor B., Conroy, Jennie L., Padron, Adrian, Meade, Julie A., Xiao, Jingbo, Hu, Xin, Dulcey, Andrés E., Han, Yang, Duan, Lihua, Titus, Steve, Bryant-Genevier, Melanie, Barnaeva, Elena, Ferrer, Marc, Javitch, Jonathan A., Beuming, Thijs, Shi, Lei, Southall, Noel T., Marugan, Juan J., Sibley, David R.
منشور في 2014

Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis.

بواسطة Frankowski, Kevin J., Wang, Chen, Patnaik, Samarjit, Schoenen, Frank J., Southall, Noel, Li, Dandan, Teper, Yaroslav, Sun, Wei, Kandela, Irawati, Hu, Deqing, Dextras, Christopher, Knotts, Zachary, Bian, Yansong, Norton, John, Titus, Steve, Lewandowska, Marzena A., Wen, Yiping, Farley, Katherine I., Griner, Lesley Mathews, Sultan, Jamey, Meng, Zhaojing, Zhou, Ming, Vilimas, Tomas, Powers, Astin S., Kozlov, Serguei, Nagashima, Kunio, Quadri, Humair S., Fang, Min, Long, Charles, Khanolkar, Ojus, Chen, Warren, Kang, Jinsol, Huang, Helen, Chow, Eric, Goldberg, Esthermanya, Feldman, Coral, Xi, Romi, Kim, Hye Rim, Sahagian, Gary, Baserga, Susan J., Mazar, Andrew, Ferrer, Marc, Zheng, Wei, Shilatifard, Ali, Aubé, Jeffrey, Rudloff, Udo, Marugan, Juan Jose, Huang, Sui
الحاوية / القاعدة Sci Transl Med (2018)