A Panel of Diverse Assays to Interrogate the Interaction between Glucokinase and Glucokinase Regulatory Protein, Two Vital Proteins in Human Disease

Recent genetic and clinical evidence has implicated glucokinase regulatory protein (GKRP) in the pathogenesis of type 2 diabetes and related traits. The primary role of GKRP is to bind and inhibit hepatic glucokinase (GCK), a critically important protein in human health and disease that exerts a sig...

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Detalhes bibliográficos
Main Authors: Rees, Matthew G., Davis, Mindy I., Shen, Min, Titus, Steve, Raimondo, Anne, Barrett, Amy, Gloyn, Anna L., Collins, Francis S., Simeonov, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929664/
https://ncbi.nlm.nih.gov/pubmed/24586696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089335
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