A Panel of Diverse Assays to Interrogate the Interaction between Glucokinase and Glucokinase Regulatory Protein, Two Vital Proteins in Human Disease

Recent genetic and clinical evidence has implicated glucokinase regulatory protein (GKRP) in the pathogenesis of type 2 diabetes and related traits. The primary role of GKRP is to bind and inhibit hepatic glucokinase (GCK), a critically important protein in human health and disease that exerts a sig...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rees, Matthew G., Davis, Mindy I., Shen, Min, Titus, Steve, Raimondo, Anne, Barrett, Amy, Gloyn, Anna L., Collins, Francis S., Simeonov, Anton
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929664/
https://ncbi.nlm.nih.gov/pubmed/24586696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089335
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