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A Small Molecule Inverse Agonist for the Human Thyroid-Stimulating Hormone Receptor
Small molecule inverse agonists for the TSH receptor (TSHR) may be used as probes of the role of basal (or agonist-independent or constitutive) signaling and may have therapeutic potential as orally active drugs to inhibit basal signaling in patients with thyroid cancer and in some patients with hyp...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Endocrine Society
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903937/ https://ncbi.nlm.nih.gov/pubmed/20427476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0199 |
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