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Ligand-Induced GPR110 Activation Facilitates Axon Growth after Injury

Recovery from axonal injury is extremely difficult, especially for adult neurons. Here, we demonstrate that the activation of G-protein coupled receptor 110 (GPR110, ADGRF1) is a mechanism to stimulate axon growth after injury. N-docosahexaenoylethanolamine (synaptamide), an endogenous ligand of GPR...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kwon, Heungsun, Kevala, Karl, Xin, Hu, Patnaik, Samarjit, Marugan, Juan, Kim, Hee-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037074/
https://ncbi.nlm.nih.gov/pubmed/33806166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073386
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