Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells

MicroRNA miR-155 is an important regulatory molecule in the immune system and is highly expressed and functional in Th17 cells, a subset of CD4(+) T helper cells which are key players in autoimmune diseases. Small molecules that can modulate miR-155 may potentially provide new therapeutic avenues to...

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Vydáno v:Sci Rep
Hlavní autoři: Singh, Anju, Dashynam, Myagmarjav, Chim, Bryan, Escobar, Thelma M., Liu, Xiuhuai, Hu, Xin, Patnaik, Samarjit, Xu, Xin, Southall, Noel, Marugan, Juan, Jadhav, Ajit, Lazarevic, Vanja, Muljo, Stefan A., Ferrer, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169650/
https://ncbi.nlm.nih.gov/pubmed/34075120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90944-7
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