Lysosomal dysfunction in neurodegeneration: The role of ATP13A2/PARK9

gan Usenovic, Marija, Krainc, Dimitri
Cyhoeddwyd 2012

Zn(2+) dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulation

gan Tsunemi, Taiji, Krainc, Dimitri
Cyhoeddwyd 2014

Development of targeted therapies for Parkinson’s disease and related synucleinopathies

gan Sybertz, Edmund, Krainc, Dimitri
Cyhoeddwyd 2014

LRRK2 phosphorylation of auxilin mediates synaptic defects in dopaminergic neurons from patients with Parkinson’s disease

gan Nguyen, Maria, Krainc, Dimitri
Cyhoeddwyd yn Proc Natl Acad Sci U S A (2018)

Untangling alpha synuclein fibrils by graphene quantum dots

gan Ysselstein, Daniel, Krainc, Dimitri
Cyhoeddwyd yn Mov Disord (2018)

Lysosomal trafficking defects link Parkinson’s disease with Gaucher’s disease

gan Wong, Yvette C., Krainc, Dimitri
Cyhoeddwyd yn Mov Disord (2016)

The role of dopamine in the pathogenesis of GBA1-linked Parkinson’s disease

gan Burbulla, Lena F., Krainc, Dimitri
Cyhoeddwyd yn Neurobiol Dis (2019)

ATP13A2/PARK9 Regulates Secretion of Exosomes and α-Synuclein

gan Tsunemi, Taiji, Hamada, Kana, Krainc, Dimitri
Cyhoeddwyd yn J Neurosci (2014)

Mutant Huntingtin Is Secreted via a Late Endosomal/Lysosomal Unconventional Secretory Pathway

gan Trajkovic, Katarina, Jeong, Hyunkyung, Krainc, Dimitri
Cyhoeddwyd yn J Neurosci (2017)

Mutant Huntingtin Secretion in Neuro2A Cells and Rat Primary Cortical Neurons

gan Trajkovic, Katarina, Jeong, Hyunkyung, Krainc, Dimitri
Cyhoeddwyd yn Bio Protoc (2018)

Organoid and Pluripotent Stem Cells in Parkinson’s Disease Modeling: An Expert View on their Value to Drug Discovery

gan Marotta, Nick, Kim, Soojin, Krainc, Dimitri
Cyhoeddwyd yn Expert Opin Drug Discov (2020)

Molecular Mechanisms of α-Synuclein and GBA1 in Parkinson’s Disease

gan Stojkovska, Iva, Krainc, Dimitri, Mazzulli, Joseph R.
Cyhoeddwyd yn Cell Tissue Res (2017)

Mitochondria-lysosome contacts regulate mitochondrial fission via Rab7 GTP hydrolysis

gan Wong, Yvette C., Ysselstein, Daniel, Krainc, Dimitri
Cyhoeddwyd yn Nature (2018)

Emerging Links Between Pediatric Lysosomal Storage Diseases and Adult Parkinsonism

gan Ysselstein, Daniel, Shulman, Joshua M., Krainc, Dimitri
Cyhoeddwyd yn Mov Disord (2019)

Lysosomal Regulation of Inter-mitochondrial Contact Fate and Motility in Charcot-Marie-Tooth Type 2

gan Wong, Yvette C., Peng, Wesley, Krainc, Dimitri
Cyhoeddwyd yn Dev Cell (2019)

Mitochondria-lysosome contacts regulate mitochondrial Ca(2+) dynamics via lysosomal TRPML1

gan Peng, Wesley, Wong, Yvette C., Krainc, Dimitri
Cyhoeddwyd yn Proc Natl Acad Sci U S A (2020)

The Convergence of Alpha-Synuclein, Mitochondrial, and Lysosomal Pathways in Vulnerability of Midbrain Dopaminergic Neurons in Parkinson’s Disease

gan Minakaki, Georgia, Krainc, Dimitri, Burbulla, Lena F.
Cyhoeddwyd yn Front Cell Dev Biol (2020)

Fluctuations in cell density alter protein markers of multiple cellular compartments, confounding experimental outcomes

gan Trajkovic, Katarina, Valdez, Clarissa, Ysselstein, Daniel, Krainc, Dimitri
Cyhoeddwyd yn PLoS One (2019)

Preserving Lysosomal Function in the Aging Brain: Insights from Neurodegeneration

gan Peng, Wesley, Minakaki, Georgia, Nguyen, Maria, Krainc, Dimitri
Cyhoeddwyd yn Neurotherapeutics (2019)

Correction to: Preserving Lysosomal Function in the Aging Brain: Insights from Neurodegeneration

gan Peng, Wesley, Minakaki, Georgia, Nguyen, Maria, Krainc, Dimitri
Cyhoeddwyd yn Neurotherapeutics (2019)