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Lysosomal dysfunction in neurodegeneration: The role of ATP13A2/PARK9
Neuronal homeostasis and survival critically depend on an efficient autophagy-lysosomal degradation pathway, especially since neurons cannot reduce the concentration of misfolded proteins and damaged organelles by cell division. While increasing evidence implicates lysosomal dysfunction in the patho...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427268/ https://ncbi.nlm.nih.gov/pubmed/22561922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.20256 |
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