Deficiency of ATP13A2 Leads to Lysosomal Dysfunction, α-Synuclein Accumulation, and Neurotoxicity

The autophagy-lysosomal pathway plays an important role in the clearance of long-lived proteins and dysfunctional organelles. Lysosomal dysfunction has been implicated in several neurodegenerative disorders including Parkinson's disease and related synucleinopathies that are characterized by ac...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Usenovic, Marija, Tresse, Emilie, Mazzulli, Joseph R., Taylor, J. Paul, Krainc, Dimitri
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462811/
https://ncbi.nlm.nih.gov/pubmed/22442086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5575-11.2012
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados