Deficiency of ATP13A2 Leads to Lysosomal Dysfunction, α-Synuclein Accumulation, and Neurotoxicity

The autophagy-lysosomal pathway plays an important role in the clearance of long-lived proteins and dysfunctional organelles. Lysosomal dysfunction has been implicated in several neurodegenerative disorders including Parkinson's disease and related synucleinopathies that are characterized by ac...

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Detaylı Bibliyografya
Asıl Yazarlar: Usenovic, Marija, Tresse, Emilie, Mazzulli, Joseph R., Taylor, J. Paul, Krainc, Dimitri
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2012
Konular:
Brief Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462811/
https://ncbi.nlm.nih.gov/pubmed/22442086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5575-11.2012
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