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Lysosomal trafficking defects link Parkinson’s disease with Gaucher’s disease
Lysosomal dysfunction has been implicated in multiple diseases including lysosomal storage disorders such as Gaucher’s disease, in which loss-of-function mutations in the GBA1 gene encoding the lysosomal hydrolase β-glucocerebrosidase (GCase) result in lipid substrate accumulation. In Parkinson’s di...
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| Publicado no: | Mov Disord |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5957289/ https://ncbi.nlm.nih.gov/pubmed/27619775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.26802 |
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