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Mitochondria-lysosome contacts regulate mitochondrial fission via Rab7 GTP hydrolysis
Both mitochondria and lysosomes are essential for maintaining cellular homeostasis, and dysfunction of both organelles has been observed in multiple diseases(1–4). Mitochondria are highly dynamic and undergo fission and fusion to maintain a functional mitochondrial network, which drives cellular met...
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| Опубликовано в: : | Nature |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6209448/ https://ncbi.nlm.nih.gov/pubmed/29364868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25486 |
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