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Mitochondria-lysosome contacts regulate mitochondrial fission via Rab7 GTP hydrolysis

Both mitochondria and lysosomes are essential for maintaining cellular homeostasis, and dysfunction of both organelles has been observed in multiple diseases(1–4). Mitochondria are highly dynamic and undergo fission and fusion to maintain a functional mitochondrial network, which drives cellular met...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nature
Auteurs principaux: Wong, Yvette C., Ysselstein, Daniel, Krainc, Dimitri
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209448/
https://ncbi.nlm.nih.gov/pubmed/29364868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25486
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