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Mitochondria-lysosome contacts regulate mitochondrial Ca(2+) dynamics via lysosomal TRPML1

Mitochondria and lysosomes are critical for cellular homeostasis, and dysfunction of both organelles has been implicated in numerous diseases. Recently, interorganelle contacts between mitochondria and lysosomes were identified and found to regulate mitochondrial dynamics. However, whether mitochond...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Peng, Wesley, Wong, Yvette C., Krainc, Dimitri
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430993/
https://ncbi.nlm.nih.gov/pubmed/32703809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003236117
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