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Mitochondria-lysosome contacts regulate mitochondrial Ca(2+) dynamics via lysosomal TRPML1

Mitochondria and lysosomes are critical for cellular homeostasis, and dysfunction of both organelles has been implicated in numerous diseases. Recently, interorganelle contacts between mitochondria and lysosomes were identified and found to regulate mitochondrial dynamics. However, whether mitochond...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Peng, Wesley, Wong, Yvette C., Krainc, Dimitri
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430993/
https://ncbi.nlm.nih.gov/pubmed/32703809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003236117
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