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The lysosomal Ca(2+) release channel TRPML1 regulates lysosome size by activating calmodulin

Intracellular lysosomal membrane trafficking, including fusion and fission, is crucial for cellular homeostasis and normal cell function. Both fusion and fission of lysosomal membrane are accompanied by lysosomal Ca(2+) release. We recently have demonstrated that the lysosomal Ca(2+) release channel...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cao, Qi, Yang, Yiming, Zhong, Xi Zoë, Dong, Xian-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437247/
https://ncbi.nlm.nih.gov/pubmed/28360104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.772160
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