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The lysosomal Ca(2+) release channel TRPML1 regulates lysosome size by activating calmodulin

Intracellular lysosomal membrane trafficking, including fusion and fission, is crucial for cellular homeostasis and normal cell function. Both fusion and fission of lysosomal membrane are accompanied by lysosomal Ca(2+) release. We recently have demonstrated that the lysosomal Ca(2+) release channel...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Cao, Qi, Yang, Yiming, Zhong, Xi Zoë, Dong, Xian-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437247/
https://ncbi.nlm.nih.gov/pubmed/28360104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.772160
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