The Type IV Mucolipidosis-Associated Protein TRPML1 is an Endo-lysosomal Iron Release Channel

TRPML1 (mucolipin-1/MCOLN1) is predicted to be an intracellular late endosomal and lysosomal ion channel protein belonging to the mucolipin subfamily of Transient Receptor Potential (TRP) proteins (1–3). Mutations in the human TRPML1 gene cause mucolipidosis type IV disease (ML4) (4, 5). ML4 patient...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nature
Auteurs principaux: Dong, Xian-ping, Cheng, Xiping, Mills, Eric, Delling, Markus, Wang, Fudi, Kurz, Tino, Xu, Haoxing
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301259/
https://ncbi.nlm.nih.gov/pubmed/18794901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07311
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