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The Type IV Mucolipidosis-Associated Protein TRPML1 is an Endo-lysosomal Iron Release Channel
TRPML1 (mucolipin-1/MCOLN1) is predicted to be an intracellular late endosomal and lysosomal ion channel protein belonging to the mucolipin subfamily of Transient Receptor Potential (TRP) proteins (1–3). Mutations in the human TRPML1 gene cause mucolipidosis type IV disease (ML4) (4, 5). ML4 patient...
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| Publicado no: | Nature |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301259/ https://ncbi.nlm.nih.gov/pubmed/18794901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07311 |
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