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Molecular Mechanisms of α-Synuclein and GBA1 in Parkinson’s Disease

Parkinson’s disease (PD) is a neurodegenerative movement disorder characterized pathologically by the presence of Lewy bodies comprised of insoluble alpha-synuclein. Pathological, clinical and genetic studies demonstrate that mutations in the GBA1 gene, which encodes the lysosomal enzyme glucocerebr...

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Publicat a:Cell Tissue Res
Autors principals: Stojkovska, Iva, Krainc, Dimitri, Mazzulli, Joseph R.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916529/
https://ncbi.nlm.nih.gov/pubmed/29064079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-017-2704-y
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