Glucosylsphingosine Promotes α-Synuclein Pathology in Mutant GBA-Associated Parkinson's Disease

Glucocerebrosidase 1 (GBA) mutations responsible for Gaucher disease (GD) are the most common genetic risk factor for Parkinson's disease (PD). Although the genetic link between GD and PD is well established, the underlying molecular mechanism(s) are not well understood. We propose that glucosy...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Taguchi, Yumiko V., Liu, Jun, Ruan, Jiapeng, Pacheco, Joshua, Zhang, Xiaokui, Abbasi, Justin, Keutzer, Joan, Mistry, Pramod K., Chandra, Sreeganga S.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2017
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628407/
https://ncbi.nlm.nih.gov/pubmed/28847804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1525-17.2017
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