Glucosylsphingosine Promotes α-Synuclein Pathology in Mutant GBA-Associated Parkinson's Disease

Glucocerebrosidase 1 (GBA) mutations responsible for Gaucher disease (GD) are the most common genetic risk factor for Parkinson's disease (PD). Although the genetic link between GD and PD is well established, the underlying molecular mechanism(s) are not well understood. We propose that glucosy...

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Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Taguchi, Yumiko V., Liu, Jun, Ruan, Jiapeng, Pacheco, Joshua, Zhang, Xiaokui, Abbasi, Justin, Keutzer, Joan, Mistry, Pramod K., Chandra, Sreeganga S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2017
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628407/
https://ncbi.nlm.nih.gov/pubmed/28847804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1525-17.2017
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