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Glucosylsphingosine is a key Biomarker of Gaucher Disease

Gaucher disease (GD) leads to accumulation of glucosylceramide (GL1) and its deacylated lysolipid, glucosylsphingosine (lyso-GL1) which is implicated in mediating immune dysregulation and skeletal disease. The aim of our study was to assess plasma Lyso-GL1 as a biomarker of GD and its response to th...

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Detalhes bibliográficos
Publicado no:Am J Hematol
Main Authors: Murugesan, Vagishwari, Chuang, Wei-Lien, Liu, Jun, Lischuk, Andrew, Kacena, Katherine, Lin, Haiqun, Pastores, Gregory M, Yang, Ruhua, Keutzer, Joan, Zhang, Kate, Mistry, Pramod K
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234703/
https://ncbi.nlm.nih.gov/pubmed/27441734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.24491
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