Glucosylsphingosine Promotes α-Synuclein Pathology in Mutant GBA-Associated Parkinson's Disease

Glucocerebrosidase 1 (GBA) mutations responsible for Gaucher disease (GD) are the most common genetic risk factor for Parkinson's disease (PD). Although the genetic link between GD and PD is well established, the underlying molecular mechanism(s) are not well understood. We propose that glucosy...

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Опубликовано в: :J Neurosci
Главные авторы: Taguchi, Yumiko V., Liu, Jun, Ruan, Jiapeng, Pacheco, Joshua, Zhang, Xiaokui, Abbasi, Justin, Keutzer, Joan, Mistry, Pramod K., Chandra, Sreeganga S.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2017
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Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628407/
https://ncbi.nlm.nih.gov/pubmed/28847804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1525-17.2017
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