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Detection of pathological alpha-synuclein aggregates in human iPSC-derived neurons and tissue
The accumulation of proteins into insoluble aggregates is a common feature of several neurodegenerative diseases. Aggregated α-synuclein is a major component of Lewy bodies that pathologically define Parkinson's disease (PD). Here, we present methods for the detection of pathogenic conformation...
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| Publicado no: | STAR Protoc |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7941090/ https://ncbi.nlm.nih.gov/pubmed/33733241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100372 |
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