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Using Human iPSC-Derived Neurons to Model TAU Aggregation
Alzheimer’s disease and frontotemporal dementia are amongst the most common forms of dementia characterized by the formation and deposition of abnormal TAU in the brain. In order to develop a translational human TAU aggregation model suitable for screening, we transduced TAU harboring the pro-aggreg...
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| 發表在: | PLoS One |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4697850/ https://ncbi.nlm.nih.gov/pubmed/26720731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146127 |
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