Using Human iPSC-Derived Neurons to Model TAU Aggregation

Alzheimer’s disease and frontotemporal dementia are amongst the most common forms of dementia characterized by the formation and deposition of abnormal TAU in the brain. In order to develop a translational human TAU aggregation model suitable for screening, we transduced TAU harboring the pro-aggreg...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Verheyen, An, Diels, Annick, Dijkmans, Joyce, Oyelami, Tutu, Meneghello, Giulia, Mertens, Liesbeth, Versweyveld, Sofie, Borgers, Marianne, Buist, Arjan, Peeters, Pieter, Cik, Miroslav
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697850/
https://ncbi.nlm.nih.gov/pubmed/26720731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146127
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