Using Human iPSC-Derived Neurons to Model TAU Aggregation

Alzheimer’s disease and frontotemporal dementia are amongst the most common forms of dementia characterized by the formation and deposition of abnormal TAU in the brain. In order to develop a translational human TAU aggregation model suitable for screening, we transduced TAU harboring the pro-aggreg...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Verheyen, An, Diels, Annick, Dijkmans, Joyce, Oyelami, Tutu, Meneghello, Giulia, Mertens, Liesbeth, Versweyveld, Sofie, Borgers, Marianne, Buist, Arjan, Peeters, Pieter, Cik, Miroslav
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697850/
https://ncbi.nlm.nih.gov/pubmed/26720731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146127
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