Suppressors of Cytokine Signaling (SOCS) in T cell differentiation, maturation, and function

Por Palmer, Douglas C., Restifo, Nicholas P.
Publicado em 2009

Glucocorticoids Do Not Inhibit Antitumor Activity of Activated CD8(+) T Cells

Por Hinrichs, Christian S., Palmer, Douglas C., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2005

The in vivo expansion rate of properly stimulated transferred CD8(+) T cells exceeds that of an aggressively growing mouse tumor

Por Hwang, Leroy N., Yu, Zhiya, Palmer, Douglas C., Restifo, Nicholas P.
Publicado em 2006

Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy

Por Klebanoff, Christopher A, Khong, Hung T, Antony, Paul A, Palmer, Douglas C, Restifo, Nicholas P
Publicado em 2005

Programming tumor-reactive effector memory CD8(+) T cells in vitro obviates the requirement for in vivo vaccination

Por Klebanoff, Christopher A., Yu, Zhiya, Hwang, Leroy N., Palmer, Douglas C., Gattinoni, Luca, Restifo, Nicholas P.
Publicado em 2009

Sensitization of B16 tumor cells with a CXCR4 antagonist increases the efficacy of immunotherapy for established lung metastases

Por Lee, Chih-hung, Kakinuma, Takashi, Wang, Julia, Zhang, Hong, Palmer, Douglas C., Restifo, Nicholas P., Hwang, Sam T.
Publicado em 2006

Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8(+) T cells

Por Wrzesinski, Claudia, Paulos, Chrystal M., Gattinoni, Luca, Palmer, Douglas C., Kaiser, Andrew, Yu, Zhiya, Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2007

High-Efficiency Transfection of Primary Human and Mouse T Lymphocytes Using RNA Electroporation

Por Zhao, Yangbing, Zheng, Zhili, Cohen, Cyrille J., Gattinoni, Luca, Palmer, Douglas C., Restifo, Nicholas P., Rosenberg, Steven A., Morgan, Richard A.
Publicado em 2005

Cross-priming utilizes antigen not available to the direct presentation pathway

Por Donohue, Keri B, Grant, Jean M, Tewalt, Eric F, Palmer, Douglas C, Theoret, Marc R, Restifo, Nicholas P, Norbury, Christopher C
Publicado em 2006

Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells

Por Wrzesinski, Claudia, Paulos, Chrystal M., Kaiser, Andrew, Muranski, Pawel, Palmer, Douglas C., Gattinoni, Luca, Yu, Zhiya, Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2010

Viral Sequestration of Antigen Subverts Cross Presentation to CD8(+) T Cells

Por Tewalt, Eric F., Grant, Jean M., Granger, Erica L., Palmer, Douglas C., Heuss, Neal D., Gregerson, Dale S., Restifo, Nicholas P., Norbury, Christopher C.
Publicado em 2009

Immunologic ignorance of vascular endothelial cells expressing minor histocompatibility antigen

Por Bolinger, Beatrice, Krebs, Philippe, Tian, Yinghua, Engeler, Daniel, Scandella, Elke, Miller, Simone, Palmer, Douglas C., Restifo, Nicholas P., Clavien, Pierre-Alain, Ludewig, Burkhard
Publicado em 2008

CTLA-4 dysregulation of self/tumor-reactive CD8(+) T-cell function is CD4(+) T-cell dependent

Por Gattinoni, Luca, Ranganathan, Anju, Surman, Deborah R., Palmer, Douglas C., Antony, Paul A., Theoret, Marc R., Heimann, David M., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2006

IFN-γ-receptor signaling ameliorates transplant vasculopathy through attenuation of CD8(+) T-cell-mediated injury of vascular endothelial cells

Por Bolinger, Beatrice, Engeler, Daniel, Krebs, Philippe, Miller, Simone, Firner, Sonja, Hoffmann, Matthias, Palmer, Douglas C., Restifo, Nicholas P., Tian, Yinghua, Clavien, Pierre-Alain, Ludewig, Burkhard
Publicado em 2010

Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8(+) T cells

Por Gattinoni, Luca, Klebanoff, Christopher A., Palmer, Douglas C., Wrzesinski, Claudia, Kerstann, Keith, Yu, Zhiya, Finkelstein, Steven E., Theoret, Marc R., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2005

Identification of the Genomic Insertion Site of Pmel-1 TCR α and β Transgenes by Next-Generation Sequencing

Por Ji, Yun, Abrams, Natalie, Zhu, Wei, Salinas, Eddie, Yu, Zhiya, Palmer, Douglas C., Jailwala, Parthav, Franco, Zulmarie, Roychoudhuri, Rahul, Stahlberg, Eric, Gattinoni, Luca, Restifo, Nicholas P.
Publicado em 2014

Interleukin-2-Dependent Mechanisms of Tolerance and Immunity In Vivo

Por Antony, Paul A., Paulos, Chrystal M., Ahmadzadeh, Mojgan, Akpinarli, Akgül, Palmer, Douglas C., Sato, Noriko, Kaiser, Andrew, Heinrichs, Christian, Klebanoff, Christopher A., Tagaya, Yutaka, Restifo, Nicholas P.
Publicado em 2006

IL-2 and IL-21 confer opposing differentiation programs to CD8(+) T cells for adoptive immunotherapy

Por Hinrichs, Christian S., Spolski, Rosanne, Paulos, Chrystal M., Gattinoni, Luca, Kerstann, Keith W., Palmer, Douglas C., Klebanoff, Christopher A., Rosenberg, Steven A., Leonard, Warren J., Restifo, Nicholas P.
Publicado em 2008

Adoptive transfer of allogeneic tumor-specific T cells mediates effective regression of large tumors across major histocompatibility barriers

Por Boni, Andrea, Muranski, Pawel, Cassard, Lydie, Wrzesinski, Claudia, Paulos, Chrystal M., Palmer, Douglas C., Gattinoni, Luca, Hinrichs, Christian S., Chan, Chi-Chao, Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2008

Wnt signaling arrests effector T cell differentiation and generates CD8(+) memory stem cells

Por Gattinoni, Luca, Zhong, Xiao-Song, Palmer, Douglas C, Ji, Yun, Hinrichs, Christian S, Yu, Zhiya, Wrzesinski, Claudia, Boni, Andrea, Cassard, Lydie, Church, Lindsay, Paulos, Chrystal M, Muranski, Pawel, Restifo, Nicholas P
Publicado em 2009