Viral Sequestration of Antigen Subverts Cross Presentation to CD8(+) T Cells

Virus-specific CD8(+) T cells (T(CD8+)) are initially triggered by peptide-MHC Class I complexes on the surface of professional antigen presenting cells (pAPC). Peptide-MHC complexes are produced by two spatially distinct pathways during virus infection. Endogenous antigens synthesized within virus-...

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Bibliografiske detaljer
Main Authors: Tewalt, Eric F., Grant, Jean M., Granger, Erica L., Palmer, Douglas C., Heuss, Neal D., Gregerson, Dale S., Restifo, Nicholas P., Norbury, Christopher C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680035/
https://ncbi.nlm.nih.gov/pubmed/19478869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000457
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