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Viral Sequestration of Antigen Subverts Cross Presentation to CD8(+) T Cells
Virus-specific CD8(+) T cells (T(CD8+)) are initially triggered by peptide-MHC Class I complexes on the surface of professional antigen presenting cells (pAPC). Peptide-MHC complexes are produced by two spatially distinct pathways during virus infection. Endogenous antigens synthesized within virus-...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680035/ https://ncbi.nlm.nih.gov/pubmed/19478869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000457 |
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