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Dendritic Cell Migration Limits the Duration of CD8(+) T-Cell Priming to Peripheral Viral Antigen

CD8(+) T cells (T(CD8(+))) play a crucial role in immunity to viruses. Antiviral T(CD8(+)) are initially activated by recognition of major histocompatibility complex (MHC) class I-peptide complexes on the surface of professional antigen-presenting cells (pAPC). Migration of pAPC from the site of inf...

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Detalhes bibliográficos
Main Authors: Schell, Amanda M., Granger, Erica L., Koczot, Frank, Fischer, Matthew A., Norbury, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838146/
https://ncbi.nlm.nih.gov/pubmed/20089641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01975-09
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