Abnormal Priming of CD4(+) T Cells by Dendritic Cells Expressing Hepatitis C Virus Core and E1 Proteins

Patients infected with hepatitis C virus (HCV) have an impaired response against HCV antigens while keeping immune competence for other antigens. We hypothesized that expression of HCV proteins in infected dendritic cells (DC) might impair their antigen-presenting function, leading to a defective an...

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Bibliographische Detailangaben
Hauptverfasser: Sarobe, Pablo, Lasarte, Juan José, Casares, Noelia, López-Díaz de Cerio, Ascensión, Baixeras, Elena, Labarga, Pablo, García, Nicolás, Borrás-Cuesta, Francisco, Prieto, Jesús
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136154/
https://ncbi.nlm.nih.gov/pubmed/11967322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.10.5062-5070.2002
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