Abnormal Priming of CD4(+) T Cells by Dendritic Cells Expressing Hepatitis C Virus Core and E1 Proteins

Patients infected with hepatitis C virus (HCV) have an impaired response against HCV antigens while keeping immune competence for other antigens. We hypothesized that expression of HCV proteins in infected dendritic cells (DC) might impair their antigen-presenting function, leading to a defective an...

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Autors principals: Sarobe, Pablo, Lasarte, Juan José, Casares, Noelia, López-Díaz de Cerio, Ascensión, Baixeras, Elena, Labarga, Pablo, García, Nicolás, Borrás-Cuesta, Francisco, Prieto, Jesús
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC136154/
https://ncbi.nlm.nih.gov/pubmed/11967322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.10.5062-5070.2002
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