Upregulation of Indoleamine 2,3-Dioxygenase in Hepatitis C Virus Infection

Indoleamine 2,3-dioxygenase (IDO) is induced by proinflammatory cytokines and by CTLA-4-expressing T cells and constitutes an important mediator of peripheral immune tolerance. In chronic hepatitis C, we found upregulation of IDO expression in the liver and an increased serum kynurenine/tryptophan r...

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Detalhes bibliográficos
Main Authors: Larrea, Esther, Riezu-Boj, José I., Gil-Guerrero, Lucía, Casares, Noelia, Aldabe, Rafael, Sarobe, Pablo, Civeira, María P., Heeney, Jonathan L., Rollier, Christine, Verstrepen, Babs, Wakita, Takaji, Borrás-Cuesta, Francisco, Lasarte, Juan J., Prieto, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866047/
https://ncbi.nlm.nih.gov/pubmed/17229698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02248-06
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