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Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse

Dendritic cells (DCs) are crucial for the priming of naive T cells and the initiation of adaptive immunity. Priming is initiated at a heterologous cell–cell contact, the immunological synapse (IS). While it is established that F-actin dynamics regulates signaling at the T cell side of the contact, l...

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Библиографические подробности
Опубликовано в: :J Cell Biol
Главные авторы: Leithner, Alexander, Altenburger, Lukas M., Hauschild, Robert, Assen, Frank P., Rottner, Klemens, Stradal, Theresia E.B., Diz-Muñoz, Alba, Stein, Jens V., Sixt, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: Rockefeller University Press 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863705/
https://ncbi.nlm.nih.gov/pubmed/33533935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006081
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